Thyrotoxicosis due to metastatic papillary thyroid cancer in a patient with Graves' disease

S. Basaria, Roberto Salvatori

Research output: Contribution to journalArticlepeer-review

Abstract

Thyrotoxicosis resulting from functional thyroid cancer metastases is extremely rare, and is mostly caused by follicular cancer. The lesions causing thyrotoxicosis are usually bulky and extensive. We report here a patient with Graves' disease and concomitant papillary thyroid cancer who developed metastases causing symptomatic thyrotoxicosis. His serum titers of thyroid stimulating Ig (TSIs) were elevated. We believe that TSIs were responsible for thyrotoxicosis by stimulating hormonogenesis in the metastatic lesions.

Original languageEnglish (US)
Pages (from-to)639-642
Number of pages4
JournalJournal of endocrinological investigation
Volume25
Issue number7
DOIs
StatePublished - Jan 1 2002

Keywords

  • Thyroid cancer
  • Thyrotoxicosis

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Endocrinology

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