Thyroid function abnormalities and cognitive impairment in elderly people: Results of the invecchiare in chianti study

Graziano Ceresini, Fulvio Lauretani, Marcello Maggio, Gian Paolo Ceda, Simonetta Morganti, Elisa Usberti, Carlo Chezzi, Rita Valcavi, Stefania Bandinelli, Jack M. Guralnik, Anne R. Cappola, Giorgio Valenti, Luigi Ferrucci

Research output: Contribution to journalArticle

Abstract

OBJECTIVES: To investigate thyroid function testing abnormalities in older persons and to explore the relationship between thyroid dysfunction and cognition. DESIGN: Cross-sectional. SETTING: Community-based. PARTICIPANTS: One thousand one hundred seventy-one men and women aged 23 to 102. MEASUREMENTS: Thyroid function was evaluated by measuring plasma concentrations of thyrotropin (TSH), free thyroxine (FT4), and free triiodothyronine (FT3). Cognition was evaluated using the Mini-Mental State Examination (MMSE). Prevalence of overt and subclinical thyroid dysfunction was evaluated in different age groups (

Original languageEnglish (US)
Pages (from-to)89-93
Number of pages5
JournalJournal of the American Geriatrics Society
Volume57
Issue number1
DOIs
StatePublished - Jan 2009
Externally publishedYes

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Keywords

  • Aging
  • Cognition
  • Thyroid function

ASJC Scopus subject areas

  • Geriatrics and Gerontology

Cite this

Ceresini, G., Lauretani, F., Maggio, M., Ceda, G. P., Morganti, S., Usberti, E., Chezzi, C., Valcavi, R., Bandinelli, S., Guralnik, J. M., Cappola, A. R., Valenti, G., & Ferrucci, L. (2009). Thyroid function abnormalities and cognitive impairment in elderly people: Results of the invecchiare in chianti study. Journal of the American Geriatrics Society, 57(1), 89-93. https://doi.org/10.1111/j.1532-5415.2008.02080.x