TY - JOUR
T1 - Thymic muscle cells bear acetylcholine receptors
T2 - Possible relation to myasthenia gravis
AU - Kao, Ing
AU - Drachman, Daniel B.
PY - 1977/1/1
Y1 - 1977/1/1
N2 - Culture of dissociated thymus from rats and humans yielded cells identical to skeletal muscle with respect to morphology, contractility, electrophysiological properties, and the presence of acetylcholine receptors. These cells, strategically located in the thymus, may play a role in initiation of the autoimmune response against acetylcholine receptors, which is characteristic of myasthenia gravis.
AB - Culture of dissociated thymus from rats and humans yielded cells identical to skeletal muscle with respect to morphology, contractility, electrophysiological properties, and the presence of acetylcholine receptors. These cells, strategically located in the thymus, may play a role in initiation of the autoimmune response against acetylcholine receptors, which is characteristic of myasthenia gravis.
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U2 - 10.1126/science.831257
DO - 10.1126/science.831257
M3 - Article
C2 - 831257
AN - SCOPUS:0017329788
SN - 0036-8075
VL - 195
SP - 74
EP - 75
JO - Science
JF - Science
IS - 4273
ER -