Thymic muscle cells bear acetylcholine receptors: Possible relation to myasthenia gravis

Research output: Contribution to journalArticlepeer-review

Abstract

Culture of dissociated thymus from rats and humans yielded cells identical to skeletal muscle with respect to morphology, contractility, electrophysiological properties, and the presence of acetylcholine receptors. These cells, strategically located in the thymus, may play a role in initiation of the autoimmune response against acetylcholine receptors, which is characteristic of myasthenia gravis.

Original languageEnglish (US)
Pages (from-to)74-75
Number of pages2
JournalScience
Volume195
Issue number4273
DOIs
StatePublished - Jan 1 1977

ASJC Scopus subject areas

  • General

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