Thromboprophylaxie en neurochirurgie et en neurotraumatologie intracrânienne

Translated title of the contribution: Thromboprophylaxis in neurosurgery and head trauma

J. F. Payen, T. Faillot, G. Audibert, M. C. Vergnes, J. L. Bosson, B. Lestienne, C. Bernard, N. Bruder

Research output: Contribution to journalArticle


The incidence of deep vein thrombosis (DVT) is between 20 and 35% using contrast venography, with a rate of symptomatic DVT between 2.3 and 6% in neurosurgery without any prophylaxis. The risk of DVT is poorly evaluated in head injured patients but is around 5%. Specific risk factors in neurosurgery are: a motor deficit, a meningioma or malignant tumour, a large tumour, age over 60 years, surgery lasting more than 4 hours, a chemotherapy. The benefit of mechanical methods or low molecular weight heparin (LMWH) for the prevention of DVP in neurosurgery is demonstrated (grade A). Each method decreases the risk by about 50%. A postoperative prophylaxis with a LMWH does not seem to increase the risk of intracranial bleeding (grade C). There is no demonstrated benefit to begin a prophylaxis with LMWH before the intervention. The duration of the prophylaxis is 7 to 10 days but this has not been scientifically determined.

Translated title of the contributionThromboprophylaxis in neurosurgery and head trauma
Original languageFrench
Pages (from-to)921-927
Number of pages7
JournalAnnales francaises d'anesthesie et de reanimation
Issue number8
StatePublished - Aug 1 2005


  • Craniotomy
  • Deep vein thrombosis
  • Heparin
  • Neurosurgery
  • Venous thromboembolism

ASJC Scopus subject areas

  • Anesthesiology and Pain Medicine

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  • Cite this

    Payen, J. F., Faillot, T., Audibert, G., Vergnes, M. C., Bosson, J. L., Lestienne, B., Bernard, C., & Bruder, N. (2005). Thromboprophylaxie en neurochirurgie et en neurotraumatologie intracrânienne. Annales francaises d'anesthesie et de reanimation, 24(8), 921-927.