Thromboprophylaxie en neurochirurgie et en neurotraumatologie intracrânienne

J. F. Payen; T. Faillot; G. Audibert; M. C. Vergnes; J. L. Bosson; B. Lestienne; C. Bernard; N. Bruder

doi:10.1016/j.annfar.2005.05.012

Thromboprophylaxie en neurochirurgie et en neurotraumatologie intracrânienne

Translated title of the contribution: Thromboprophylaxis in neurosurgery and head trauma

J. F. Payen, T. Faillot, G. Audibert, M. C. Vergnes, J. L. Bosson, B. Lestienne, C. Bernard, N. Bruder

Research output: Contribution to journal › Article › peer-review

11 Scopus citations

Abstract

The incidence of deep vein thrombosis (DVT) is between 20 and 35% using contrast venography, with a rate of symptomatic DVT between 2.3 and 6% in neurosurgery without any prophylaxis. The risk of DVT is poorly evaluated in head injured patients but is around 5%. Specific risk factors in neurosurgery are: a motor deficit, a meningioma or malignant tumour, a large tumour, age over 60 years, surgery lasting more than 4 hours, a chemotherapy. The benefit of mechanical methods or low molecular weight heparin (LMWH) for the prevention of DVP in neurosurgery is demonstrated (grade A). Each method decreases the risk by about 50%. A postoperative prophylaxis with a LMWH does not seem to increase the risk of intracranial bleeding (grade C). There is no demonstrated benefit to begin a prophylaxis with LMWH before the intervention. The duration of the prophylaxis is 7 to 10 days but this has not been scientifically determined.

Translated title of the contribution	Thromboprophylaxis in neurosurgery and head trauma
Original language	French
Pages (from-to)	921-927
Number of pages	7
Journal	Annales Francaises d'Anesthesie et de Reanimation
Volume	24
Issue number	8
DOIs	https://doi.org/10.1016/j.annfar.2005.05.012
State	Published - Aug 2005
Externally published	Yes

Keywords

Craniotomy
Deep vein thrombosis
Heparin
Neurosurgery
Venous thromboembolism

ASJC Scopus subject areas

Anesthesiology and Pain Medicine

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10.1016/j.annfar.2005.05.012

Cite this

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title = "Thromboprophylaxie en neurochirurgie et en neurotraumatologie intracr{\^a}nienne",

abstract = "The incidence of deep vein thrombosis (DVT) is between 20 and 35% using contrast venography, with a rate of symptomatic DVT between 2.3 and 6% in neurosurgery without any prophylaxis. The risk of DVT is poorly evaluated in head injured patients but is around 5%. Specific risk factors in neurosurgery are: a motor deficit, a meningioma or malignant tumour, a large tumour, age over 60 years, surgery lasting more than 4 hours, a chemotherapy. The benefit of mechanical methods or low molecular weight heparin (LMWH) for the prevention of DVP in neurosurgery is demonstrated (grade A). Each method decreases the risk by about 50%. A postoperative prophylaxis with a LMWH does not seem to increase the risk of intracranial bleeding (grade C). There is no demonstrated benefit to begin a prophylaxis with LMWH before the intervention. The duration of the prophylaxis is 7 to 10 days but this has not been scientifically determined.",

keywords = "Craniotomy, Deep vein thrombosis, Heparin, Neurosurgery, Venous thromboembolism",

author = "Payen, {J. F.} and T. Faillot and G. Audibert and Vergnes, {M. C.} and Bosson, {J. L.} and B. Lestienne and C. Bernard and N. Bruder",

year = "2005",

month = aug,

doi = "10.1016/j.annfar.2005.05.012",

language = "French",

volume = "24",

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AU - Payen, J. F.

AU - Faillot, T.

AU - Audibert, G.

AU - Vergnes, M. C.

AU - Bosson, J. L.

AU - Lestienne, B.

AU - Bernard, C.

AU - Bruder, N.

PY - 2005/8

Y1 - 2005/8

N2 - The incidence of deep vein thrombosis (DVT) is between 20 and 35% using contrast venography, with a rate of symptomatic DVT between 2.3 and 6% in neurosurgery without any prophylaxis. The risk of DVT is poorly evaluated in head injured patients but is around 5%. Specific risk factors in neurosurgery are: a motor deficit, a meningioma or malignant tumour, a large tumour, age over 60 years, surgery lasting more than 4 hours, a chemotherapy. The benefit of mechanical methods or low molecular weight heparin (LMWH) for the prevention of DVP in neurosurgery is demonstrated (grade A). Each method decreases the risk by about 50%. A postoperative prophylaxis with a LMWH does not seem to increase the risk of intracranial bleeding (grade C). There is no demonstrated benefit to begin a prophylaxis with LMWH before the intervention. The duration of the prophylaxis is 7 to 10 days but this has not been scientifically determined.

AB - The incidence of deep vein thrombosis (DVT) is between 20 and 35% using contrast venography, with a rate of symptomatic DVT between 2.3 and 6% in neurosurgery without any prophylaxis. The risk of DVT is poorly evaluated in head injured patients but is around 5%. Specific risk factors in neurosurgery are: a motor deficit, a meningioma or malignant tumour, a large tumour, age over 60 years, surgery lasting more than 4 hours, a chemotherapy. The benefit of mechanical methods or low molecular weight heparin (LMWH) for the prevention of DVP in neurosurgery is demonstrated (grade A). Each method decreases the risk by about 50%. A postoperative prophylaxis with a LMWH does not seem to increase the risk of intracranial bleeding (grade C). There is no demonstrated benefit to begin a prophylaxis with LMWH before the intervention. The duration of the prophylaxis is 7 to 10 days but this has not been scientifically determined.

KW - Craniotomy

KW - Deep vein thrombosis

KW - Heparin

KW - Neurosurgery

KW - Venous thromboembolism

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ER -

Thromboprophylaxie en neurochirurgie et en neurotraumatologie intracrânienne

Abstract

Keywords

ASJC Scopus subject areas

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