Three new diterpenoids from Leonurus japonicus

Zhi Ke Liu, Da Rong Wu, Yi Ming Shi, Ting Zeng, Shao Hua Liu, Xue Du, Yong Jun Dang, Wei Lie Xiao, Han Dong Sun

Research output: Contribution to journalArticle

Abstract

Phytochemical investigation of the aerial parts of Leonurus japonicus led to the isolation of one unusual clerodane diterpenoid, leojaponin A (1), characterized by a C4-C7 oxa-bridge, and two new labdane diterpenoids, leojaponins B (2) and C (3). The structures of these new compounds were determined based on extensive 1D and 2D NMR spectroscopic data. To the best of our knowledge, compound 1 is the first clerodane diterpenoid obtained from Leonurus. japonicus. All of them were evaluated for their cytotoxicity.

Original languageEnglish (US)
Pages (from-to)677-679
Number of pages3
JournalChinese Chemical Letters
Volume25
Issue number5
DOIs
StatePublished - 2014
Externally publishedYes

Fingerprint

Clerodane Diterpenes
Diterpenes
Phytochemicals
Cytotoxicity
Nuclear magnetic resonance
Antennas

Keywords

  • Leojaponin A
  • Leojaponin B
  • Leojaponin C
  • Leonurus japonicus

ASJC Scopus subject areas

  • Chemistry(all)

Cite this

Liu, Z. K., Wu, D. R., Shi, Y. M., Zeng, T., Liu, S. H., Du, X., ... Sun, H. D. (2014). Three new diterpenoids from Leonurus japonicus. Chinese Chemical Letters, 25(5), 677-679. https://doi.org/10.1016/j.cclet.2014.01.047

Three new diterpenoids from Leonurus japonicus. / Liu, Zhi Ke; Wu, Da Rong; Shi, Yi Ming; Zeng, Ting; Liu, Shao Hua; Du, Xue; Dang, Yong Jun; Xiao, Wei Lie; Sun, Han Dong.

In: Chinese Chemical Letters, Vol. 25, No. 5, 2014, p. 677-679.

Research output: Contribution to journalArticle

Liu, ZK, Wu, DR, Shi, YM, Zeng, T, Liu, SH, Du, X, Dang, YJ, Xiao, WL & Sun, HD 2014, 'Three new diterpenoids from Leonurus japonicus', Chinese Chemical Letters, vol. 25, no. 5, pp. 677-679. https://doi.org/10.1016/j.cclet.2014.01.047
Liu, Zhi Ke ; Wu, Da Rong ; Shi, Yi Ming ; Zeng, Ting ; Liu, Shao Hua ; Du, Xue ; Dang, Yong Jun ; Xiao, Wei Lie ; Sun, Han Dong. / Three new diterpenoids from Leonurus japonicus. In: Chinese Chemical Letters. 2014 ; Vol. 25, No. 5. pp. 677-679.
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