Three forms of dominant amyloid neuropathy

George Henry Sack, K. W. Dumars, K. S. Gummerson, A. Law, V. A. McKusick

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

While a common name and similar pathogenic features unite the genetic amyloidoses, these disorders generally can be distinguished by distinctive clinical patterns. This is particularly apparent when large kindreds are compared. The authors present instructive examples of members from kindreds of the three most clearly defined autosomal dominant types of amyloid neuropathy. Salient features, important for diagnosis, prognosis, and management, distinguish each type. Growing understanding of the biochemical changes in the amyloidoses aids appreciation of these disorders even as it provides an opportunity to study mechanisms which may be important in normal protein metabolism.

Original languageEnglish (US)
Title of host publicationJohns Hopkins Medical Journal
Pages239-247
Number of pages9
Volume149
Edition6
StatePublished - 1981

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Amyloid Neuropathies
Amyloidosis
Inborn Genetic Diseases
Names
Proteins

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Sack, G. H., Dumars, K. W., Gummerson, K. S., Law, A., & McKusick, V. A. (1981). Three forms of dominant amyloid neuropathy. In Johns Hopkins Medical Journal (6 ed., Vol. 149, pp. 239-247)

Three forms of dominant amyloid neuropathy. / Sack, George Henry; Dumars, K. W.; Gummerson, K. S.; Law, A.; McKusick, V. A.

Johns Hopkins Medical Journal. Vol. 149 6. ed. 1981. p. 239-247.

Research output: Chapter in Book/Report/Conference proceedingChapter

Sack, GH, Dumars, KW, Gummerson, KS, Law, A & McKusick, VA 1981, Three forms of dominant amyloid neuropathy. in Johns Hopkins Medical Journal. 6 edn, vol. 149, pp. 239-247.
Sack GH, Dumars KW, Gummerson KS, Law A, McKusick VA. Three forms of dominant amyloid neuropathy. In Johns Hopkins Medical Journal. 6 ed. Vol. 149. 1981. p. 239-247
Sack, George Henry ; Dumars, K. W. ; Gummerson, K. S. ; Law, A. ; McKusick, V. A. / Three forms of dominant amyloid neuropathy. Johns Hopkins Medical Journal. Vol. 149 6. ed. 1981. pp. 239-247
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