TY - JOUR
T1 - Three-dimensional volumetric MRI with isotropic resolution
T2 - improved speed of acquisition, spatial resolution and assessment of lesion conspicuity in patients with recurrent soft tissue sarcoma
AU - Ahlawat, Shivani
AU - Morris, Carol
AU - Fayad, Laura M.
PY - 2016/5/1
Y1 - 2016/5/1
N2 - Background: To assess the acquisition speed, lesion conspicuity, and inter-observer agreement associated with volumetric T1-weighted MR sequences with isotropic resolution for detecting recurrent soft-tissue sarcoma (STS). Methods: Fifteen subjects with histologically proven recurrent STS underwent MRI, including axial and coronal T1-weighted spin echo (T1-WSE) (5-mm slice thickness) and coronal 3D volumetric T1-weighted (fat-suppressed, volume-interpolated, breath-hold examination; repetition time/echo time, 3.7/1.4 ms; flip angle, 9.5°; 1-mm slice thickness) sequences before and after intravenous contrast administration. Subtraction imaging and multiplanar reformations (MPRs) were performed. Acquisition times for T1-WSE in two planes and 3D sequences were reported. Two radiologists reviewed images for quality (>50 % artifacts, 25–50 % artifacts, <25 % artifacts, and no substantial artifacts), lesion conspicuity, contrast-to-noise ratio (CNRmuscle), recurrence size, and recurrence-to-joint distance. Descriptive and intraclass correlation (ICC) statistics are given. Results: Mean acquisition times were significantly less for 3D imaging compared with 2-plane T1-WSE (183.6 vs 342.6 s; P = 0.012). Image quality was rated as having no substantial artifacts in 13/15 and <25 % artifacts in 2/15. Lesion conspicuity was significantly improved for subtracted versus unsubtracted images (CNRmuscle, 100 ± 138 vs 181 ± 199; P = 0.05). Mean recurrent lesion size was 2.5 cm (range, 0.7–5.7 cm), and measurements on 3D sequences offered excellent interobserver agreement (ICC, 0.98 for lesion size and 0.96 for recurrence-to-joint distance with MPR views). Conclusion: Three-dimensional volumetric sequences offer faster acquisition times, higher spatial resolution, and MPR capability compared with 2D T1-WSE for postcontrast imaging. Subtraction imaging provides higher lesion conspicuity for detecting recurrent STS in skeletal muscle, with excellent interobserver agreement between readers.
AB - Background: To assess the acquisition speed, lesion conspicuity, and inter-observer agreement associated with volumetric T1-weighted MR sequences with isotropic resolution for detecting recurrent soft-tissue sarcoma (STS). Methods: Fifteen subjects with histologically proven recurrent STS underwent MRI, including axial and coronal T1-weighted spin echo (T1-WSE) (5-mm slice thickness) and coronal 3D volumetric T1-weighted (fat-suppressed, volume-interpolated, breath-hold examination; repetition time/echo time, 3.7/1.4 ms; flip angle, 9.5°; 1-mm slice thickness) sequences before and after intravenous contrast administration. Subtraction imaging and multiplanar reformations (MPRs) were performed. Acquisition times for T1-WSE in two planes and 3D sequences were reported. Two radiologists reviewed images for quality (>50 % artifacts, 25–50 % artifacts, <25 % artifacts, and no substantial artifacts), lesion conspicuity, contrast-to-noise ratio (CNRmuscle), recurrence size, and recurrence-to-joint distance. Descriptive and intraclass correlation (ICC) statistics are given. Results: Mean acquisition times were significantly less for 3D imaging compared with 2-plane T1-WSE (183.6 vs 342.6 s; P = 0.012). Image quality was rated as having no substantial artifacts in 13/15 and <25 % artifacts in 2/15. Lesion conspicuity was significantly improved for subtracted versus unsubtracted images (CNRmuscle, 100 ± 138 vs 181 ± 199; P = 0.05). Mean recurrent lesion size was 2.5 cm (range, 0.7–5.7 cm), and measurements on 3D sequences offered excellent interobserver agreement (ICC, 0.98 for lesion size and 0.96 for recurrence-to-joint distance with MPR views). Conclusion: Three-dimensional volumetric sequences offer faster acquisition times, higher spatial resolution, and MPR capability compared with 2D T1-WSE for postcontrast imaging. Subtraction imaging provides higher lesion conspicuity for detecting recurrent STS in skeletal muscle, with excellent interobserver agreement between readers.
KW - 3D volumetric MR sequences
KW - Recurrent soft-tissue sarcoma
KW - Subtraction imaging
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U2 - 10.1007/s00256-016-2348-0
DO - 10.1007/s00256-016-2348-0
M3 - Article
C2 - 26897528
AN - SCOPUS:84958749144
SN - 0364-2348
VL - 45
SP - 645
EP - 652
JO - Skeletal Radiology
JF - Skeletal Radiology
IS - 5
ER -