Three dimensional visualization of proteins in cellular interactions

Colin R.F. Monks; Patricia J. Crossno; George Davidson; Constantine Pavlakos; Abraham Kupfer; Claudio Silva; Brian Wylie

doi:10.1109/visual.1996.568133

Three dimensional visualization of proteins in cellular interactions

Colin R.F. Monks, Patricia J. Crossno, George Davidson, Constantine Pavlakos, Abraham Kupfer, Claudio Silva, Brian Wylie

Research output: Contribution to conference › Paper › peer-review

7 Scopus citations

Abstract

In researching the communication mechanisms between cells of the immune system, visualization of proteins in three dimensions can be used to determine which proteins are capable of interacting with one another at a given time by showing their spatial colocality. Volume data sets are created using digital confocal immunofluorescence microscopy. A variety of visualization approaches are then used to examine the interactions. These include volume rendering, isosurface extraction, and virtual reality. Based on our experiences, we have concluded that no single one of these approaches provides a complete solution for visualizing biological data. However, in combination, their respective strengths complement one another to provide an understanding of the data.

Original language	English (US)
Pages	363-366
Number of pages	4
DOIs	https://doi.org/10.1109/visual.1996.568133
State	Published - 1996
Externally published	Yes
Event	Proceedings of the 1996 IEEE Visualization Conference - San Francisco, CA, USA Duration: Oct 27 1996 → Nov 1 1996

Other

Other	Proceedings of the 1996 IEEE Visualization Conference
City	San Francisco, CA, USA
Period	10/27/96 → 11/1/96

ASJC Scopus subject areas

Software
General Computer Science
General Engineering
Computer Graphics and Computer-Aided Design

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10.1109/visual.1996.568133

Cite this

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title = "Three dimensional visualization of proteins in cellular interactions",

abstract = "In researching the communication mechanisms between cells of the immune system, visualization of proteins in three dimensions can be used to determine which proteins are capable of interacting with one another at a given time by showing their spatial colocality. Volume data sets are created using digital confocal immunofluorescence microscopy. A variety of visualization approaches are then used to examine the interactions. These include volume rendering, isosurface extraction, and virtual reality. Based on our experiences, we have concluded that no single one of these approaches provides a complete solution for visualizing biological data. However, in combination, their respective strengths complement one another to provide an understanding of the data.",

author = "Monks, {Colin R.F.} and Crossno, {Patricia J.} and George Davidson and Constantine Pavlakos and Abraham Kupfer and Claudio Silva and Brian Wylie",

year = "1996",

doi = "10.1109/visual.1996.568133",

language = "English (US)",

pages = "363--366",

}

TY - CONF

T1 - Three dimensional visualization of proteins in cellular interactions

AU - Monks, Colin R.F.

AU - Crossno, Patricia J.

AU - Davidson, George

AU - Pavlakos, Constantine

AU - Kupfer, Abraham

AU - Silva, Claudio

AU - Wylie, Brian

PY - 1996

Y1 - 1996

N2 - In researching the communication mechanisms between cells of the immune system, visualization of proteins in three dimensions can be used to determine which proteins are capable of interacting with one another at a given time by showing their spatial colocality. Volume data sets are created using digital confocal immunofluorescence microscopy. A variety of visualization approaches are then used to examine the interactions. These include volume rendering, isosurface extraction, and virtual reality. Based on our experiences, we have concluded that no single one of these approaches provides a complete solution for visualizing biological data. However, in combination, their respective strengths complement one another to provide an understanding of the data.

AB - In researching the communication mechanisms between cells of the immune system, visualization of proteins in three dimensions can be used to determine which proteins are capable of interacting with one another at a given time by showing their spatial colocality. Volume data sets are created using digital confocal immunofluorescence microscopy. A variety of visualization approaches are then used to examine the interactions. These include volume rendering, isosurface extraction, and virtual reality. Based on our experiences, we have concluded that no single one of these approaches provides a complete solution for visualizing biological data. However, in combination, their respective strengths complement one another to provide an understanding of the data.

UR - http://www.scopus.com/inward/record.url?scp=0030411074&partnerID=8YFLogxK

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DO - 10.1109/visual.1996.568133

M3 - Paper

AN - SCOPUS:0030411074

SP - 363

EP - 366

T2 - Proceedings of the 1996 IEEE Visualization Conference

Y2 - 27 October 1996 through 1 November 1996

ER -

Three dimensional visualization of proteins in cellular interactions

Abstract

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ASJC Scopus subject areas

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