Three dimensional reconstruction of the components of the carotid plaque from standard CT medical images

Dipankar Biswas, Francis Loth, Susan McCormick, Hisham Bassiouny

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

The present study compares plaque and calcium volumes between sixteen diseased human carotid arteries. Half were from symptomatic patients, and half were from asymptomatic patients. In-house software was developed for the 3-D reconstruction of the plaque components from computerized tomography (CT) images. Results revealed higher mean total volume (TV) in the symptomatic group compared to the asymptomatic group. In contrast, the mean ratio of calcium volume (CV) to TV was lower for the symptomatic group compared to the asymptomatic group. This shows that symptomatic patients have a significantly greater plaque burden with minimal plaque calcification. The process of acquiring the data helped understand what tools/features are needed to conduct this work. One important feature of this software is the ability to create automated regions of interest (ROI) in addition to simple manual selection/modification of the ROIs in a GUI environment.

Original languageEnglish (US)
Title of host publicationASME 2011 Summer Bioengineering Conference, SBC 2011
Pages35-36
Number of pages2
EditionPARTS A AND B
DOIs
StatePublished - 2011
Externally publishedYes
EventASME 2011 Summer Bioengineering Conference, SBC 2011 - Farmington, PA, United States
Duration: Jun 22 2011Jun 25 2011

Publication series

NameASME 2011 Summer Bioengineering Conference, SBC 2011
NumberPARTS A AND B

Other

OtherASME 2011 Summer Bioengineering Conference, SBC 2011
Country/TerritoryUnited States
CityFarmington, PA
Period6/22/116/25/11

Keywords

  • Calcium
  • Carotid artery
  • CT image
  • Plaque volume

ASJC Scopus subject areas

  • Bioengineering

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