@inproceedings{a45bc50a14e24057bff50c9059db2ab7,
title = "Three-dimensional heat-induced echo-strain imaging for monitoring high-intensity acoustic ablation",
abstract = "Three dimensional heat-induced echo-strain imaging is a potentially useful tool for monitoring the formation of thermal lesions during ablative therapy. Heat-induced echo-strain, known as thermal strain, is due to the changes in the speed of propagating ultrasound signals and to tissue expansion during heat deposition. This paper presents a complete system for targeting and intraoperative monitoring of thermal ablation by high intensity focused acoustic applicators. A special software interface has been developed to enable motor motion control of 3D mechanical probes and rapid acquisition of 3D-RF data (ultrasound raw data after the beam-forming unit). Ex-vivo phantom and tissue studies were performed in a controlled laboratory environment. While B-mode ultrasound does not clearly identify the development of either necrotic lesions or the deposited thermal dose, the proposed 3D echo-strain imaging can visualize these changes, demonstrating agreement with temperature sensor readings and gross-pathology. Current results also demonstrate feasibility for realtime computation through a parallelized implementation for the algorithm used. Typically, 125 frames per volume can be processed in less than a second. We also demonstrate motion compensation that can account for shift within frames due to either tissue movement or positional error in the US 3D imaging probe.",
keywords = "3D ultrasound, Ablation monitoring, Echo-strain, High intensity focused ultrasound (HIFU), Parallelization, Therapy, Thermal imaging",
author = "Boctor, {Emad M.} and Nishikant Deshmukh and Maria, {S. Ayad} and Clyde Clarke and Kris Dickie and Choti, {Michael A.} and Burdette, {Everette C.}",
year = "2009",
doi = "10.1117/12.811287",
language = "English (US)",
isbn = "9780819475169",
series = "Progress in Biomedical Optics and Imaging - Proceedings of SPIE",
booktitle = "Medical Imaging 2009",
note = "Medical Imaging 2009: Ultrasonic Imaging and Signal Processing ; Conference date: 08-02-2009 Through 09-02-2009",
}