Thioridazine for treatment of tuberculosis: Promises and pitfalls

Noton K. Dutta, Petros C. Karakousis

Research output: Contribution to journalComment/debatepeer-review

Abstract

The articles by De Knegt et al. and Singh et al. in a recent issue of this Journal address one of the current debates regarding the potential role of thioridazine in the treatment of tuberculosis. This commentary presents a summary of the available evidence, and, emphasizing the need for further research, asks the question: "How far can we go in repurposing thioridazine?"

Original languageEnglish (US)
Pages (from-to)708-711
Number of pages4
JournalTuberculosis
Volume94
Issue number6
DOIs
StatePublished - Dec 1 2014

Keywords

  • Adjunctive therapy
  • Animal model
  • Efflux pump inhibitor
  • Latent TB
  • Mycobacterium tuberculosis
  • Thioridazine

ASJC Scopus subject areas

  • Microbiology
  • Immunology
  • Microbiology (medical)
  • Infectious Diseases

Fingerprint Dive into the research topics of 'Thioridazine for treatment of tuberculosis: Promises and pitfalls'. Together they form a unique fingerprint.

Cite this