Thermal lesion conspicuity following interstitial radiofrequency thermal tumor ablation in humans: A comparison of STIR, turbo spin-echo T2-weighted, and contrast-enhanced T1-weighted MR images at 0.2 T

Andrik J. Aschoff, Niusha Rafie, John A. Jesberger, Jeffrey L. Duerk, Jonathan S. Lewin

Research output: Contribution to journalArticle

Abstract

The purpose of this study was to compare the contrast between radiofrequency (RF) thermal liver lesions and surrounding tissue in T2-weighted turbo spin-echo sequences (TSE T2), short T1 inversion recovery techniques (STIR), and contrast-enhanced (CE) T1-weighted spin-echo images. Nineteen RF thermal ablations were performed on eight patients with metastatic liver tumors. After ablation, contrast-to-noise ratios (CNRs) were calculated between mean signal amplitudes from three regions of interest (ROI) (lesion, surrounding edema, and normal tissue) using TSE T2-weighted, STIR, and contrast-enhanced T1-weighted (CE T1) sequences for each lesion. CHRs between the thermal lesion and normal liver tissue for both TSE T2-weighted (mean 0.9) and STIR (2.0) images were significantly lower than for CE T1-weighted (8.4) images (t-test, α = 0.05). However, CNRs between edema rim and the core of the thermal lesion for both TSE T2-weighted (8.1) and STIR images (7.2) were not significantly different (t-test, α = 0.05) from CHRs between lesion and normal tissue for CE T1-weighted images (8.4), nor was the CNR between edema rim and normal tissue for both TSE T2-weighted (10.3) and STIR (9.8) images. Although the edema was not visible on CE T1-weighted images, 18 of 19 lesions (94.7%) were surrounded by a hyparintense rim on TSE T2-weighted or STIR images. Both TSE T2-weighted and STIR sequences represent valid techniques for repeatable assessment of RF thermal lesions. (C) 2000 Wiley-Liss, Inc.

Original languageEnglish (US)
Pages (from-to)584-589
Number of pages6
JournalJournal of Magnetic Resonance Imaging
Volume12
Issue number4
DOIs
StatePublished - 2000
Externally publishedYes

Fingerprint

Hot Temperature
Edema
Noise
Neoplasms
Liver

Keywords

  • Interstitial thermotherapy
  • Intervention
  • Liver
  • MRI
  • Radiofrequency

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology

Cite this

Thermal lesion conspicuity following interstitial radiofrequency thermal tumor ablation in humans : A comparison of STIR, turbo spin-echo T2-weighted, and contrast-enhanced T1-weighted MR images at 0.2 T. / Aschoff, Andrik J.; Rafie, Niusha; Jesberger, John A.; Duerk, Jeffrey L.; Lewin, Jonathan S.

In: Journal of Magnetic Resonance Imaging, Vol. 12, No. 4, 2000, p. 584-589.

Research output: Contribution to journalArticle

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abstract = "The purpose of this study was to compare the contrast between radiofrequency (RF) thermal liver lesions and surrounding tissue in T2-weighted turbo spin-echo sequences (TSE T2), short T1 inversion recovery techniques (STIR), and contrast-enhanced (CE) T1-weighted spin-echo images. Nineteen RF thermal ablations were performed on eight patients with metastatic liver tumors. After ablation, contrast-to-noise ratios (CNRs) were calculated between mean signal amplitudes from three regions of interest (ROI) (lesion, surrounding edema, and normal tissue) using TSE T2-weighted, STIR, and contrast-enhanced T1-weighted (CE T1) sequences for each lesion. CHRs between the thermal lesion and normal liver tissue for both TSE T2-weighted (mean 0.9) and STIR (2.0) images were significantly lower than for CE T1-weighted (8.4) images (t-test, α = 0.05). However, CNRs between edema rim and the core of the thermal lesion for both TSE T2-weighted (8.1) and STIR images (7.2) were not significantly different (t-test, α = 0.05) from CHRs between lesion and normal tissue for CE T1-weighted images (8.4), nor was the CNR between edema rim and normal tissue for both TSE T2-weighted (10.3) and STIR (9.8) images. Although the edema was not visible on CE T1-weighted images, 18 of 19 lesions (94.7{\%}) were surrounded by a hyparintense rim on TSE T2-weighted or STIR images. Both TSE T2-weighted and STIR sequences represent valid techniques for repeatable assessment of RF thermal lesions. (C) 2000 Wiley-Liss, Inc.",
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AU - Duerk, Jeffrey L.

AU - Lewin, Jonathan S.

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