There is no overkill in biochemistry: Har Gobind Khorana, a pioneer in membrane biology

Sadashiva Karnik, Sriram Subramaniam

Research output: Contribution to journalArticle

Abstract

Har Gobind Khorana pioneered study of transmembrane proteins at highest resolution possible through the application of biochemical techniques. His research on bacteriorhodopsin, a retinal based light driven proton pump from Halobacterium halobium spanned a range of ground breaking studies from membrane reconstitution, complete denaturation and refolding of a polytopic membrane protein, gene synthesis combined with genetically-directed protein modification and protein dynamic/kinetic analysis. His courage for tackling tough biochemical problems through enormous enthusiasm, building of a multi disciplinary team and maintain focus is a lesson for generations to come.

Original languageEnglish (US)
Pages (from-to)1157-1164
Number of pages8
JournalResonance
Volume17
Issue number12
DOIs
StatePublished - 2012
Externally publishedYes

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biochemistry
biology

Keywords

  • bacteriorhodopsin
  • Gobind Khorana
  • light-induced signaling
  • transmembrane proteins

ASJC Scopus subject areas

  • General
  • Education

Cite this

There is no overkill in biochemistry : Har Gobind Khorana, a pioneer in membrane biology. / Karnik, Sadashiva; Subramaniam, Sriram.

In: Resonance, Vol. 17, No. 12, 2012, p. 1157-1164.

Research output: Contribution to journalArticle

Karnik, Sadashiva ; Subramaniam, Sriram. / There is no overkill in biochemistry : Har Gobind Khorana, a pioneer in membrane biology. In: Resonance. 2012 ; Vol. 17, No. 12. pp. 1157-1164.
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