Abstract
Infection with HCV is common in HIV-infected patients and is an increasingly important public health problem. The medical management of hepatitis C in HIV-infected patients is complicated by immune suppression, potential drug interactions and toxicities, and the relative paucity of health-care providers with expertise in the management of both diseases. Nonetheless, there are now data to support the safety, tolerability and efficacy of hepatitis C treatment with peginterferon plus ribavirin in HIV-infected patients, and the impetus to treat these patients is, therefore, strong. Although the standard of care for the treatment of hepatitis C in HIV-infected patients has been more clearly defined, the delivery of care for hepatitis C remains inconsistent in many settings. The development and implementation of single-center multidisciplinary programs that combine the expertise of HIV specialists, hepatologists, gastroenterologists, psychiatrists, and addiction specialists, are needed to improve hepatitis C treatment outcomes in HIV-infected patients. This review considers the management of HCV infection in HIV-infected patients.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 223-231 |
| Number of pages | 9 |
| Journal | Nature Clinical Practice Gastroenterology and Hepatology |
| Volume | 2 |
| Issue number | 5 |
| DOIs | |
| State | Published - May 2005 |
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Keywords
- HCV
- HIV
- Interferon
- Ribavirin
- Treatment
ASJC Scopus subject areas
- Gastroenterology
- Hepatology
Cite this
Therapy insight : Management of hepatitis C in patients coinfected with HIV. / Sulkowski, Mark.
In: Nature Clinical Practice Gastroenterology and Hepatology, Vol. 2, No. 5, 05.2005, p. 223-231.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Therapy insight
T2 - Management of hepatitis C in patients coinfected with HIV
AU - Sulkowski, Mark
PY - 2005/5
Y1 - 2005/5
N2 - Infection with HCV is common in HIV-infected patients and is an increasingly important public health problem. The medical management of hepatitis C in HIV-infected patients is complicated by immune suppression, potential drug interactions and toxicities, and the relative paucity of health-care providers with expertise in the management of both diseases. Nonetheless, there are now data to support the safety, tolerability and efficacy of hepatitis C treatment with peginterferon plus ribavirin in HIV-infected patients, and the impetus to treat these patients is, therefore, strong. Although the standard of care for the treatment of hepatitis C in HIV-infected patients has been more clearly defined, the delivery of care for hepatitis C remains inconsistent in many settings. The development and implementation of single-center multidisciplinary programs that combine the expertise of HIV specialists, hepatologists, gastroenterologists, psychiatrists, and addiction specialists, are needed to improve hepatitis C treatment outcomes in HIV-infected patients. This review considers the management of HCV infection in HIV-infected patients.
AB - Infection with HCV is common in HIV-infected patients and is an increasingly important public health problem. The medical management of hepatitis C in HIV-infected patients is complicated by immune suppression, potential drug interactions and toxicities, and the relative paucity of health-care providers with expertise in the management of both diseases. Nonetheless, there are now data to support the safety, tolerability and efficacy of hepatitis C treatment with peginterferon plus ribavirin in HIV-infected patients, and the impetus to treat these patients is, therefore, strong. Although the standard of care for the treatment of hepatitis C in HIV-infected patients has been more clearly defined, the delivery of care for hepatitis C remains inconsistent in many settings. The development and implementation of single-center multidisciplinary programs that combine the expertise of HIV specialists, hepatologists, gastroenterologists, psychiatrists, and addiction specialists, are needed to improve hepatitis C treatment outcomes in HIV-infected patients. This review considers the management of HCV infection in HIV-infected patients.
KW - HCV
KW - HIV
KW - Interferon
KW - Ribavirin
KW - Treatment
UR - http://www.scopus.com/inward/record.url?scp=20444498277&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=20444498277&partnerID=8YFLogxK
U2 - 10.1038/ncpgasthep0170
DO - 10.1038/ncpgasthep0170
M3 - Article
C2 - 16265205
AN - SCOPUS:20444498277
VL - 2
SP - 223
EP - 231
JO - Nature Reviews Gastroenterology and Hepatology
JF - Nature Reviews Gastroenterology and Hepatology
SN - 1759-5045
IS - 5
ER -