Therapeutic plasma exchange in neurology: 2012

Irene Cortese, David R. Cornblath

Research output: Contribution to journalArticlepeer-review


In treating neuroimmunological diseases, neurologists have a number of different drugs to choose from ranging from corticosteroids to IVIg to more specific cell based therapies, the latter most frequently from the world of oncology. In some diseases, therapeutic plasma exchange, a procedure rather than a drug, is used. The most obvious advantage of therapeutic plasma exchange is the usually rapid onset of action presumably due to removal of pathogenic auto-antibodies. In some diseases, a single course of therapeutic plasma exchange is used while in others prolonged treatment with therapeutic plasma exchange is used. This article will review the use of therapeutic plasma exchange in neurology and will draw heavily upon recent consensus statements from the American Society for Apheresis and the American Academy of Neurology and by Cochrane reviews. J. Clin. Apheresis 28:16-19, 2013. © 2013 Wiley Periodicals, Inc.

Original languageEnglish (US)
Pages (from-to)16-19
Number of pages4
JournalJournal of Clinical Apheresis
Issue number1
StatePublished - Feb 2013


  • CIDP
  • Guillain-Barré syndrome
  • apheresis
  • myasthenia gravis
  • neurologic indications
  • plasmapheresis
  • therapeutic plasma exchange

ASJC Scopus subject areas

  • Hematology


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