TY - JOUR
T1 - Therapeutic horizons for amyotrophic lateral sclerosis
AU - Rothstein, Jeffrey D.
N1 - Funding Information:
The author's work is supported by the National Institutes of Health (NS33958), the Muscular Dystrophy Association, the ALS Association, and the Cal Ripkin/Lou Gehrig Fund for Neuromuscular Research,
PY - 1996/10
Y1 - 1996/10
N2 - Recent theories on the pathogenesis of motor neuron disease and research on motor neuron injury have resulted in new putative therapies, which include treatment with various neurotrophic factors, antioxidants and anti-excitotoxicity agents. Clinical and preclinical studies have now provided the first agents that reproducibly alter the course of amyotrophic lateral sclerosis.
AB - Recent theories on the pathogenesis of motor neuron disease and research on motor neuron injury have resulted in new putative therapies, which include treatment with various neurotrophic factors, antioxidants and anti-excitotoxicity agents. Clinical and preclinical studies have now provided the first agents that reproducibly alter the course of amyotrophic lateral sclerosis.
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U2 - 10.1016/S0959-4388(96)80103-6
DO - 10.1016/S0959-4388(96)80103-6
M3 - Article
C2 - 8937834
AN - SCOPUS:0030273704
SN - 0959-4388
VL - 6
SP - 679
EP - 687
JO - Current Opinion in Neurobiology
JF - Current Opinion in Neurobiology
IS - 5
ER -