Therapeutic effects of oral zinc in acute and persistent diarrhea in children in developing countries: Pooled analysis of randomized controlled trials

Z. A. Bhutta, S. M. Bird, Robert E Black, K. H. Brown, J. M. Gardner, A. Hidayat, F. Khatun, R. Martorell, N. X. Ninh, M. E. Penny, J. L. Rosado, S. K. Roy, M. Ruel, S. Sazawal, A. Shankar

Research output: Contribution to journalArticle

Abstract

Background: Zinc deficiency is prevalent in children in developing countries. Supplemental zinc provides therapeutic benefits in diarrhea. Objective: We sought to measure the effect of supplemental zinc given with oral rehydration therapy during recovery from acute or persistent diarrhea. Design: We conducted pooled analyses including all available published and unpublished randomized controlled trials of the effects of supplementary oral zinc in children aged

Original languageEnglish (US)
Pages (from-to)1516-1522
Number of pages7
JournalAmerican Journal of Clinical Nutrition
Volume72
Issue number6
StatePublished - 2000

Fingerprint

Therapeutic Uses
Developing Countries
Zinc
developing countries
Diarrhea
diarrhea
mouth
Randomized Controlled Trials
zinc
therapeutics
oral rehydration
Fluid Therapy
Therapeutics

Keywords

  • Children
  • Developing countries
  • Diarrhea
  • Diarrheal disease
  • Infants
  • Malnutrition
  • Meta-analysis
  • Nutrition
  • Randomized controlled trial
  • Zinc
  • Zinc deficiency
  • Zinc supplementation

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Food Science

Cite this

Therapeutic effects of oral zinc in acute and persistent diarrhea in children in developing countries : Pooled analysis of randomized controlled trials. / Bhutta, Z. A.; Bird, S. M.; Black, Robert E; Brown, K. H.; Gardner, J. M.; Hidayat, A.; Khatun, F.; Martorell, R.; Ninh, N. X.; Penny, M. E.; Rosado, J. L.; Roy, S. K.; Ruel, M.; Sazawal, S.; Shankar, A.

In: American Journal of Clinical Nutrition, Vol. 72, No. 6, 2000, p. 1516-1522.

Research output: Contribution to journalArticle

Bhutta, ZA, Bird, SM, Black, RE, Brown, KH, Gardner, JM, Hidayat, A, Khatun, F, Martorell, R, Ninh, NX, Penny, ME, Rosado, JL, Roy, SK, Ruel, M, Sazawal, S & Shankar, A 2000, 'Therapeutic effects of oral zinc in acute and persistent diarrhea in children in developing countries: Pooled analysis of randomized controlled trials', American Journal of Clinical Nutrition, vol. 72, no. 6, pp. 1516-1522.
Bhutta, Z. A. ; Bird, S. M. ; Black, Robert E ; Brown, K. H. ; Gardner, J. M. ; Hidayat, A. ; Khatun, F. ; Martorell, R. ; Ninh, N. X. ; Penny, M. E. ; Rosado, J. L. ; Roy, S. K. ; Ruel, M. ; Sazawal, S. ; Shankar, A. / Therapeutic effects of oral zinc in acute and persistent diarrhea in children in developing countries : Pooled analysis of randomized controlled trials. In: American Journal of Clinical Nutrition. 2000 ; Vol. 72, No. 6. pp. 1516-1522.
@article{b8dd00cc2692480082d3689535e6472a,
title = "Therapeutic effects of oral zinc in acute and persistent diarrhea in children in developing countries: Pooled analysis of randomized controlled trials",
abstract = "Background: Zinc deficiency is prevalent in children in developing countries. Supplemental zinc provides therapeutic benefits in diarrhea. Objective: We sought to measure the effect of supplemental zinc given with oral rehydration therapy during recovery from acute or persistent diarrhea. Design: We conducted pooled analyses including all available published and unpublished randomized controlled trials of the effects of supplementary oral zinc in children aged",
keywords = "Children, Developing countries, Diarrhea, Diarrheal disease, Infants, Malnutrition, Meta-analysis, Nutrition, Randomized controlled trial, Zinc, Zinc deficiency, Zinc supplementation",
author = "Bhutta, {Z. A.} and Bird, {S. M.} and Black, {Robert E} and Brown, {K. H.} and Gardner, {J. M.} and A. Hidayat and F. Khatun and R. Martorell and Ninh, {N. X.} and Penny, {M. E.} and Rosado, {J. L.} and Roy, {S. K.} and M. Ruel and S. Sazawal and A. Shankar",
year = "2000",
language = "English (US)",
volume = "72",
pages = "1516--1522",
journal = "American Journal of Clinical Nutrition",
issn = "0002-9165",
publisher = "American Society for Nutrition",
number = "6",

}

TY - JOUR

T1 - Therapeutic effects of oral zinc in acute and persistent diarrhea in children in developing countries

T2 - Pooled analysis of randomized controlled trials

AU - Bhutta, Z. A.

AU - Bird, S. M.

AU - Black, Robert E

AU - Brown, K. H.

AU - Gardner, J. M.

AU - Hidayat, A.

AU - Khatun, F.

AU - Martorell, R.

AU - Ninh, N. X.

AU - Penny, M. E.

AU - Rosado, J. L.

AU - Roy, S. K.

AU - Ruel, M.

AU - Sazawal, S.

AU - Shankar, A.

PY - 2000

Y1 - 2000

N2 - Background: Zinc deficiency is prevalent in children in developing countries. Supplemental zinc provides therapeutic benefits in diarrhea. Objective: We sought to measure the effect of supplemental zinc given with oral rehydration therapy during recovery from acute or persistent diarrhea. Design: We conducted pooled analyses including all available published and unpublished randomized controlled trials of the effects of supplementary oral zinc in children aged

AB - Background: Zinc deficiency is prevalent in children in developing countries. Supplemental zinc provides therapeutic benefits in diarrhea. Objective: We sought to measure the effect of supplemental zinc given with oral rehydration therapy during recovery from acute or persistent diarrhea. Design: We conducted pooled analyses including all available published and unpublished randomized controlled trials of the effects of supplementary oral zinc in children aged

KW - Children

KW - Developing countries

KW - Diarrhea

KW - Diarrheal disease

KW - Infants

KW - Malnutrition

KW - Meta-analysis

KW - Nutrition

KW - Randomized controlled trial

KW - Zinc

KW - Zinc deficiency

KW - Zinc supplementation

UR - http://www.scopus.com/inward/record.url?scp=0033652984&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0033652984&partnerID=8YFLogxK

M3 - Article

C2 - 11101480

AN - SCOPUS:0033652984

VL - 72

SP - 1516

EP - 1522

JO - American Journal of Clinical Nutrition

JF - American Journal of Clinical Nutrition

SN - 0002-9165

IS - 6

ER -