Therapeutic Drug Monitoring of Antiretrovirals

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Antiretroviral therapy (ART) is a primary modality for the treatment and management of HIV/AIDS. Antiretroviral (ARV) agents are associated with drug-drug interactions and high inter-individual variability. The current status of therapeutic drug monitoring (TDM) for ARV drug classes will be discussed. Additionally, first-line study regimens, consensus recommendations, and analytical methodologies will also be included in this chapter.

Original languageEnglish (US)
Title of host publicationClinical Challenges in Therapeutic Drug Monitoring: Special Populations, Physiological Conditions, and Pharmacogenomics
PublisherElsevier Inc.
Pages135-163
Number of pages29
ISBN (Electronic)9780128020524
ISBN (Print)9780128020258
DOIs
Publication statusPublished - May 17 2016

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Keywords

  • Antiretrovirals
  • HAART therapy
  • Limitations
  • Protease inhibitors
  • Therapeutic drug monitoring

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Marzinke, M. A. (2016). Therapeutic Drug Monitoring of Antiretrovirals. In Clinical Challenges in Therapeutic Drug Monitoring: Special Populations, Physiological Conditions, and Pharmacogenomics (pp. 135-163). Elsevier Inc.. https://doi.org/10.1016/B978-0-12-802025-8.00006-4