Therapeutic Drug Monitoring of Antiretrovirals

Mark A Marzinke

doi:10.1016/B978-0-12-802025-8.00006-4

Therapeutic Drug Monitoring of Antiretrovirals

Mark A Marzinke

School of Medicine

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

Antiretroviral therapy (ART) is a primary modality for the treatment and management of HIV/AIDS. Antiretroviral (ARV) agents are associated with drug-drug interactions and high inter-individual variability. The current status of therapeutic drug monitoring (TDM) for ARV drug classes will be discussed. Additionally, first-line study regimens, consensus recommendations, and analytical methodologies will also be included in this chapter.

Original language	English (US)
Title of host publication	Clinical Challenges in Therapeutic Drug Monitoring: Special Populations, Physiological Conditions, and Pharmacogenomics
Publisher	Elsevier Inc.
Pages	135-163
Number of pages	29
ISBN (Electronic)	9780128020524
ISBN (Print)	9780128020258
DOIs	https://doi.org/10.1016/B978-0-12-802025-8.00006-4
State	Published - May 17 2016

Keywords

Antiretrovirals
HAART therapy
Limitations
Protease inhibitors
Therapeutic drug monitoring

ASJC Scopus subject areas

Medicine(all)

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10.1016/B978-0-12-802025-8.00006-4

Cite this

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AB - Antiretroviral therapy (ART) is a primary modality for the treatment and management of HIV/AIDS. Antiretroviral (ARV) agents are associated with drug-drug interactions and high inter-individual variability. The current status of therapeutic drug monitoring (TDM) for ARV drug classes will be discussed. Additionally, first-line study regimens, consensus recommendations, and analytical methodologies will also be included in this chapter.

KW - Antiretrovirals

KW - HAART therapy

KW - Limitations

KW - Protease inhibitors

KW - Therapeutic drug monitoring

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BT - Clinical Challenges in Therapeutic Drug Monitoring: Special Populations, Physiological Conditions, and Pharmacogenomics

PB - Elsevier Inc.

ER -

Therapeutic Drug Monitoring of Antiretrovirals

Abstract

Keywords

ASJC Scopus subject areas

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