TY - GEN
T1 - Theoretical and experimental study of intercellular junction-induced sawtooth effect in cardiac cell-pairs
AU - Sharma, Vinod
AU - Tung, Leslie
PY - 1999/12/1
Y1 - 1999/12/1
N2 - We present an analytical expression for the sawtooth amplitude (STA) in an isolated cell-pair with junctional resistance (Rj). Experimentally, STA was estimated in isolated guinea pig cell-pairs by optically recording transmembrane potential responses (Vm) with subcellular spatial resolution. We estimated STA to be approximately 14 mV for a 10 V/cm field. From theoretical calculations, this corresponds to an Rj of approximately 22 MΩ.
AB - We present an analytical expression for the sawtooth amplitude (STA) in an isolated cell-pair with junctional resistance (Rj). Experimentally, STA was estimated in isolated guinea pig cell-pairs by optically recording transmembrane potential responses (Vm) with subcellular spatial resolution. We estimated STA to be approximately 14 mV for a 10 V/cm field. From theoretical calculations, this corresponds to an Rj of approximately 22 MΩ.
UR - http://www.scopus.com/inward/record.url?scp=0033330003&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0033330003&partnerID=8YFLogxK
M3 - Conference contribution
AN - SCOPUS:0033330003
SN - 0780356756
T3 - Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings
BT - Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings
PB - IEEE
T2 - Proceedings of the 1999 IEEE Engineering in Medicine and Biology 21st Annual Conference and the 1999 Fall Meeting of the Biomedical Engineering Society (1st Joint BMES / EMBS)
Y2 - 13 October 1999 through 16 October 1999
ER -