The World of Immunization: Achievements, Challenges, and Strategic Vision for the Next Decade

Ann Lindstrand, Thomas Cherian, Diana Chang-Blanc, Daniel Feikin, Katherine L. O'brien

Research output: Contribution to journalArticlepeer-review


Immunization is among the most cost-effective public health interventions available and is estimated to have averted at least 37 million deaths between 2000 and 2019. Since the establishment of the Expanded Programme on Immunization in 1974, global vaccination coverage increased and the coverage gap between rich and poor countries decreased. Creation of Gavi, the Vaccine Alliance, in 2000 allowed the poorest countries in the world to benefit from new, life-saving vaccines and expand the breadth of protection against an increasing number of vaccine-preventable diseases. Despite this progress, inequities in access to and uptake of vaccines persist. Opportunities to realize the full potential of vaccines are within reach but require focused, tailored and committed action by Governments and immunization stakeholders. The Immunization Agenda 2030 provides a framework for action during the next decade to attain a world where everyone, everywhere, at every age fully benefits from vaccines for good health and well-being.

Original languageEnglish (US)
Pages (from-to)S452-S467
JournalJournal of Infectious Diseases
StatePublished - Oct 1 2021
Externally publishedYes


  • EPI
  • IA2030
  • challenges
  • decade
  • history
  • immunization
  • impact
  • overview
  • vaccines
  • vision

ASJC Scopus subject areas

  • Immunology and Allergy
  • Infectious Diseases


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