The viscoelastic properties of passive eye muscle in primates. II: Testing the quasi-linear theory

Christian Quaia, Howard S. Ying, Lance M. Optican

Research output: Contribution to journalArticlepeer-review

Abstract

We have extensively investigated the mechanical properties of passive eye muscles, in vivo, in anesthetized and paralyzed monkeys. The complexity inherent in rheological measurements makes it desirable to present the results in terms of a mathematical model. Because Fung's quasi-linear viscoelastic (QLV) model has been particularly successful in capturing the viscoelastic properties of passive biological tissues, here we analyze this dataset within the framework of Fung's theory. We found that the basic properties assumed under the QLV theory (separability and superposition) are not typical of passive eye muscles. We show that some recent extensions of Fung's model can deal successfully with the lack of separability, but fail to reproduce the deviation from superposition. While appealing for their elegance, the QLV model and its descendants are not able to capture the complex mechanical properties of passive eye muscles. In particular, our measurements suggest that in a passive extraocular muscle the force does not depend on the entire length history, but to a great extent is only a function of the last elongation to which it has been subjected. It is currently unknown whether other passive biological tissues behave similarly.

Original languageEnglish (US)
Article numbere6480
JournalPloS one
Volume4
Issue number8
DOIs
StatePublished - Aug 3 2009

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Agricultural and Biological Sciences(all)
  • General

Fingerprint

Dive into the research topics of 'The viscoelastic properties of passive eye muscle in primates. II: Testing the quasi-linear theory'. Together they form a unique fingerprint.

Cite this