The Utility of EndoFLIP for Measuring Gastrojejunal Anastomosis Diameter and Distensibility in Patients Experiencing Weight Regain Post Roux-en-Y Gastric Bypass

Zadid Haq, Mohamad I. Itani, Linda Zhang, Fazel Dinary, Jad Farha, Shahem Abbarh, Venkata Akshintala, Kristen Koller, Manol Jovani, Abdellah Hedjoudje, Saowanee Ngamruengphong, Andreas Oberbach, Dilhana Badurdeen, Vivek Kumbhari

Research output: Contribution to journalArticlepeer-review

Abstract

A dilated gastrojejunal anastomosis (GJA) diameter is an independent predictor of weight regain following Roux-en-Y gastric bypass (RYGB). Despite this, there is no standardized method for GJA diameter measurement. We performed a retrospective analysis to compare endoscopic visual estimation and endoluminal functional impedance planimetry (EndoFLIP) for measuring GJA diameter in patients with weight regain post-RYGB. Visual estimation was found to overestimate GJA diameter by a mean of 4.2mm ± 4.6mm when compared with EndoFLIP. Furthermore, we identified symptomatic patients with normal GJA diameter but increased distensibility, which may represent a previously unrecognized subgroup. Our findings suggest the potential utility of EndoFLIP in the evaluation of post-RYGB weight regain and support the need for prospective studies to investigate the relationship between GJA distensibility and weight regain Graphical Abstract: [Figure not available: see fulltext.].

Original languageEnglish (US)
Pages (from-to)3353-3359
Number of pages7
JournalObesity Surgery
Volume31
Issue number7
DOIs
StatePublished - Jul 2021

Keywords

  • EndoFLIP
  • GJA diameter
  • GJA distensibility
  • RYGB
  • Weight regain

ASJC Scopus subject areas

  • Surgery
  • Endocrinology, Diabetes and Metabolism
  • Nutrition and Dietetics

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