The use of magnetic resonance imaging to track controlled drug release and transport in the brain

Bradley Reisfeld, Stephen Blackband, Vince Calhoun, Stuart Grossman, Susan Eller, Kam Leong

Research output: Contribution to journalArticle

Abstract

A method has been developed to track controlled drug release and transport in the brain. This method entails the use of a polymeric implant to release, over time, a paramagnetically labelled compound into the brain. Magnetic resonance imaging is used to determine the evolving concentration distribution. This method is well suited to other types of intracranial drug delivery systems as well as to track transport in other organs of the body.

Original languageEnglish (US)
Pages (from-to)247-252
Number of pages6
JournalMagnetic Resonance Imaging
Volume11
Issue number2
DOIs
StatePublished - 1993

Keywords

  • Brain
  • Controlled release
  • Drug transport
  • Gadolinium
  • Magnetic resonance imaging
  • Polymeric implant

ASJC Scopus subject areas

  • Biophysics
  • Biomedical Engineering
  • Radiology Nuclear Medicine and imaging

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