The use of magnetic resonance imaging to track controlled drug release and transport in the brain

Bradley Reisfeld; Stephen Blackband; Vince Calhoun; Stuart Grossman; Susan Eller; Kam Leong

doi:10.1016/0730-725X(93)90029-D

The use of magnetic resonance imaging to track controlled drug release and transport in the brain

Bradley Reisfeld, Stephen Blackband, Vince Calhoun, Stuart Grossman, Susan Eller, Kam Leong

Research output: Contribution to journal › Article › peer-review

13 Scopus citations

Abstract

A method has been developed to track controlled drug release and transport in the brain. This method entails the use of a polymeric implant to release, over time, a paramagnetically labelled compound into the brain. Magnetic resonance imaging is used to determine the evolving concentration distribution. This method is well suited to other types of intracranial drug delivery systems as well as to track transport in other organs of the body.

Original language	English (US)
Pages (from-to)	247-252
Number of pages	6
Journal	Magnetic Resonance Imaging
Volume	11
Issue number	2
DOIs	https://doi.org/10.1016/0730-725X(93)90029-D
State	Published - 1993
Externally published	Yes

Keywords

Brain
Controlled release
Drug transport
Gadolinium
Magnetic resonance imaging
Polymeric implant

ASJC Scopus subject areas

Biophysics
Biomedical Engineering
Radiology Nuclear Medicine and imaging

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10.1016/0730-725X(93)90029-D

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abstract = "A method has been developed to track controlled drug release and transport in the brain. This method entails the use of a polymeric implant to release, over time, a paramagnetically labelled compound into the brain. Magnetic resonance imaging is used to determine the evolving concentration distribution. This method is well suited to other types of intracranial drug delivery systems as well as to track transport in other organs of the body.",

keywords = "Brain, Controlled release, Drug transport, Gadolinium, Magnetic resonance imaging, Polymeric implant",

author = "Bradley Reisfeld and Stephen Blackband and Vince Calhoun and Stuart Grossman and Susan Eller and Kam Leong",

note = "Funding Information: Acknowledgments- This work was supported in part by The National Institute of Health through grants NS27961 and CA52857. Copyright: Copyright 2014 Elsevier B.V., All rights reserved.",

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AU - Calhoun, Vince

AU - Grossman, Stuart

AU - Eller, Susan

AU - Leong, Kam

N1 - Funding Information: Acknowledgments- This work was supported in part by The National Institute of Health through grants NS27961 and CA52857. Copyright: Copyright 2014 Elsevier B.V., All rights reserved.

PY - 1993

Y1 - 1993

N2 - A method has been developed to track controlled drug release and transport in the brain. This method entails the use of a polymeric implant to release, over time, a paramagnetically labelled compound into the brain. Magnetic resonance imaging is used to determine the evolving concentration distribution. This method is well suited to other types of intracranial drug delivery systems as well as to track transport in other organs of the body.

AB - A method has been developed to track controlled drug release and transport in the brain. This method entails the use of a polymeric implant to release, over time, a paramagnetically labelled compound into the brain. Magnetic resonance imaging is used to determine the evolving concentration distribution. This method is well suited to other types of intracranial drug delivery systems as well as to track transport in other organs of the body.

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KW - Drug transport

KW - Gadolinium

KW - Magnetic resonance imaging

KW - Polymeric implant

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The use of magnetic resonance imaging to track controlled drug release and transport in the brain

Abstract

Keywords

ASJC Scopus subject areas

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