The treatment of osteoarthritis of the knee with pulsed electrical stimulation

Thomas M. Zizic, K. C. Hoffman, P. A. Holt, D. S. Hungerford, J. R. O'Dell, Michael Jacobs, C. G. Lewis, C. L. Deal, J. R. Caldwell, J. G. Cholewczynski, S. M. Free

Research output: Contribution to journalArticle

Abstract

Objective. The safety and effectiveness of pulsed electrical stimulation was evaluated for the treatment of osteoarthritis (OA) of the knee. Methods. A multicenter, double blind, randomized, placebo controlled trial that enrolled 78 patients with OA of the knee incorporated 3 primary efficacy variables of patients' pain, patients' function, and physician global evaluation of patients' condition, and 6 secondary variables that included duration of morning stiffness, range of motion, knee tenderness, joint swelling, joint circumference, and walking time. Measurements were recorded at baseline and during the 4 week treatment period. Results. Patients treated with the active devices showed significantly greater improvement than the placebo group for all primary efficacy variables in comparisons of mean change from baseline to the end of treatment (p

Original languageEnglish (US)
Pages (from-to)1757-1761
Number of pages5
JournalJournal of Rheumatology
Volume22
Issue number9
StatePublished - 1995
Externally publishedYes

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Knee Osteoarthritis
Electric Stimulation
Placebos
Therapeutics
Knee Joint
Articular Range of Motion
Walking
Randomized Controlled Trials
Joints
Physicians
Safety
Pain
Equipment and Supplies

Keywords

  • ELECTRICAL STIMULATION
  • OSTEOARTHRITIS

ASJC Scopus subject areas

  • Rheumatology
  • Immunology

Cite this

Zizic, T. M., Hoffman, K. C., Holt, P. A., Hungerford, D. S., O'Dell, J. R., Jacobs, M., ... Free, S. M. (1995). The treatment of osteoarthritis of the knee with pulsed electrical stimulation. Journal of Rheumatology, 22(9), 1757-1761.

The treatment of osteoarthritis of the knee with pulsed electrical stimulation. / Zizic, Thomas M.; Hoffman, K. C.; Holt, P. A.; Hungerford, D. S.; O'Dell, J. R.; Jacobs, Michael; Lewis, C. G.; Deal, C. L.; Caldwell, J. R.; Cholewczynski, J. G.; Free, S. M.

In: Journal of Rheumatology, Vol. 22, No. 9, 1995, p. 1757-1761.

Research output: Contribution to journalArticle

Zizic, TM, Hoffman, KC, Holt, PA, Hungerford, DS, O'Dell, JR, Jacobs, M, Lewis, CG, Deal, CL, Caldwell, JR, Cholewczynski, JG & Free, SM 1995, 'The treatment of osteoarthritis of the knee with pulsed electrical stimulation', Journal of Rheumatology, vol. 22, no. 9, pp. 1757-1761.
Zizic TM, Hoffman KC, Holt PA, Hungerford DS, O'Dell JR, Jacobs M et al. The treatment of osteoarthritis of the knee with pulsed electrical stimulation. Journal of Rheumatology. 1995;22(9):1757-1761.
Zizic, Thomas M. ; Hoffman, K. C. ; Holt, P. A. ; Hungerford, D. S. ; O'Dell, J. R. ; Jacobs, Michael ; Lewis, C. G. ; Deal, C. L. ; Caldwell, J. R. ; Cholewczynski, J. G. ; Free, S. M. / The treatment of osteoarthritis of the knee with pulsed electrical stimulation. In: Journal of Rheumatology. 1995 ; Vol. 22, No. 9. pp. 1757-1761.
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