The treatment of candidemia

Mark J. Dinubile, Corrado Girmenia, Pietro Martino, Richard D. Cofsky, C. M. Tang, P. Howe, D. W. Crook, John H. Rex, John E. Bennett, Alan M. Sugar, Françoise Meunier

Research output: Contribution to journalLetterpeer-review

Abstract

To the Editor: The prospective study by Rex and colleagues (Nov. 17 issue)1 comparing amphotericin B with fluconazole for the treatment of candidemia concludes that the two treatments are equally effective. This opinion is echoed and endorsed in the accompanying editorial.2 Unfortunately, this randomized, controlled study may in some respects provide the right answer to the wrong question. It may be misconstrued as a mandate for the treatment of all patients with candidemia. Overall, patients with candidemia treated with either amphotericin B or fluconazole do not appear to have fared much better than untreated historical controls.3 I contend that no.

Original languageEnglish (US)
Pages (from-to)1100-1102
Number of pages3
JournalNew England Journal of Medicine
Volume332
Issue number16
DOIs
StatePublished - Apr 20 1995

ASJC Scopus subject areas

  • Medicine(all)

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