The thinning top: Why old people have less hair

Sashank K. Reddy; Luis A. Garza

doi:10.1038/jid.2014.172

The thinning top: Why old people have less hair

Sashank K. Reddy, Luis A. Garza

School of Medicine

Research output: Contribution to journal › Comment/debate › peer-review

3 Scopus citations

Abstract

Changes in the hair cycle underlie age-related alopecia, but the causative mechanisms have remained unclear. Chen et al. point to an imbalance between stem cell-activating and-inhibitory signals as the key determinant of age-related regenerative decline. Further, they identify a secreted protein, follistatin, that may be able to shift the balance toward renewal.

Original language	English (US)
Pages (from-to)	2068-2069
Number of pages	2
Journal	Journal of Investigative Dermatology
Volume	134
Issue number	8
DOIs	https://doi.org/10.1038/jid.2014.172
State	Published - Aug 2014

ASJC Scopus subject areas

Biochemistry
Molecular Biology
Dermatology
Cell Biology

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10.1038/jid.2014.172

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title = "The thinning top: Why old people have less hair",

abstract = "Changes in the hair cycle underlie age-related alopecia, but the causative mechanisms have remained unclear. Chen et al. point to an imbalance between stem cell-activating and-inhibitory signals as the key determinant of age-related regenerative decline. Further, they identify a secreted protein, follistatin, that may be able to shift the balance toward renewal.",

author = "Reddy, {Sashank K.} and Garza, {Luis A.}",

note = "Funding Information: LAG was supported by the National Institute of Arthritis and Musculoskeletal and Skin Diseases, part of the National Institutes of Health, under Award Number R01AR064297.",

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AU - Garza, Luis A.

N1 - Funding Information: LAG was supported by the National Institute of Arthritis and Musculoskeletal and Skin Diseases, part of the National Institutes of Health, under Award Number R01AR064297.

PY - 2014/8

Y1 - 2014/8

N2 - Changes in the hair cycle underlie age-related alopecia, but the causative mechanisms have remained unclear. Chen et al. point to an imbalance between stem cell-activating and-inhibitory signals as the key determinant of age-related regenerative decline. Further, they identify a secreted protein, follistatin, that may be able to shift the balance toward renewal.

AB - Changes in the hair cycle underlie age-related alopecia, but the causative mechanisms have remained unclear. Chen et al. point to an imbalance between stem cell-activating and-inhibitory signals as the key determinant of age-related regenerative decline. Further, they identify a secreted protein, follistatin, that may be able to shift the balance toward renewal.

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The thinning top: Why old people have less hair

Abstract

ASJC Scopus subject areas

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