The Systemic Lupus International Collaborating Clinics/American College of Rheumatology (SLICC/ACR) Damage Index for systemic lupus erythematosus international comparison

Dafna D. Gladman, Charles H. Goldsmith, Murray B. Urowitz, Paul Bacon, Paul Fortin, Ellen Ginzler, Caroline Gordon, John G. Hanly, David A. Isenberg, Michelle Petri, Ola Nived, Michael Snaith, Gunnar Sturfelt

Research output: Contribution to journalArticle

Abstract

Objective. To compare patients with systemic lupus erythematosus (SLE) from different centers with respect to demographics and Systemic Lupus International Collaborating Clinics/American College of Rheumatology Damage Index (SLICC/ACR DI) scores, and to assess whether the SLICC/ACR DI changed over time, and whether initial DI scores were related to outcome. Methods. Members of SLICC completed DI scores and patient demographics on patients followed in their centers. Information was provided at 2, 5-10, and > 10 years of followup. Data were entered on computer and analyzed on SPSS/PC+ and SAS using descriptive statistics and analysis of variance. Results. Information for 1297 patients within 2 years of first clinic visit was submitted from 8 centers. There were 1187 women and 110 men with a mean age at diagnosis of SLE of 32 years. Seven hundred sixty-two were Caucasian, 423 were black, and the remainder were of other races. There were more blacks in the American centers than in Canadian or European centers. Five centers provided information for the 3 time periods. The DI increased over time. Ninety-nine patients had died. Higher SLICC/ACR DI scores were documented in patients who went on to die. Conclusion. The SLICC/ACR DI is a valid measure for damage in SLE.

Original languageEnglish (US)
Pages (from-to)373-376
Number of pages4
JournalJournal of Rheumatology
Volume27
Issue number2
StatePublished - 2000

Keywords

  • Damage
  • International Comparison
  • SLE

ASJC Scopus subject areas

  • Rheumatology
  • Immunology and Allergy
  • Immunology

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    Gladman, D. D., Goldsmith, C. H., Urowitz, M. B., Bacon, P., Fortin, P., Ginzler, E., Gordon, C., Hanly, J. G., Isenberg, D. A., Petri, M., Nived, O., Snaith, M., & Sturfelt, G. (2000). The Systemic Lupus International Collaborating Clinics/American College of Rheumatology (SLICC/ACR) Damage Index for systemic lupus erythematosus international comparison. Journal of Rheumatology, 27(2), 373-376.