The pathophysiology of TBI can be considered as a dual insult composed of primary and secondary injuries. Growing experimental and clinical evidence suggests that disturbances of cerebral energy metabolism are a key factor in the pathogenesis of secondary cerebral damages. In addition, hormonal dysfunction after TBI, such as adrenal insuffi ciency, vasopressin, growth hormone, or thyrothropin defi ciency, can be associated with poor prognosis. A better understanding of energy metabolism and hormonal disturbances after TBI is necessary to improve the care management at the early phase of TBI.
|Original language||English (US)|
|Title of host publication||The Stress Response of Critical Illness|
|Subtitle of host publication||Metabolic and Hormonal Aspects|
|Publisher||Springer International Publishing|
|Number of pages||10|
|State||Published - Jan 1 2016|
ASJC Scopus subject areas