TY - JOUR
T1 - The small-animal radiation research platform (SARRP)
T2 - Dosimetry of a focused lens system
AU - Deng, Hua
AU - Kennedy, Christopher W.
AU - Armour, Elwood
AU - Tryggestad, Erik
AU - Ford, Eric
AU - McNutt, Todd
AU - Jiang, Licai
AU - Wong, John
PY - 2007/5/21
Y1 - 2007/5/21
N2 - A small animal radiation platform equipped with on-board cone-beam CT and conformal irradiation capabilities is being constructed for translational research. To achieve highly localized dose delivery, an x-ray lens is used to focus the broad beam from a 225 kVp x-ray tube down to a beam with a full width half maximum (FWHM) of approximately 1.5 mm in the energy range 40-80 keV. Here, we report on the dosimetric characteristics of the focused beam from the x-ray lens subsystem for high-resolution dose delivery. Using the metric of the average dose within a 1.5 mm diameter area, the dose rates at a source-to-surface distance (SSD) of 34 cm are 259 and 172 cGy min-1 at 6 mm and 2 cm depths, respectively, with an estimated uncertainty of ±5%. The per cent depth dose is approximately 56% at 2 cm depth for a beam at 34 cm SSD.
AB - A small animal radiation platform equipped with on-board cone-beam CT and conformal irradiation capabilities is being constructed for translational research. To achieve highly localized dose delivery, an x-ray lens is used to focus the broad beam from a 225 kVp x-ray tube down to a beam with a full width half maximum (FWHM) of approximately 1.5 mm in the energy range 40-80 keV. Here, we report on the dosimetric characteristics of the focused beam from the x-ray lens subsystem for high-resolution dose delivery. Using the metric of the average dose within a 1.5 mm diameter area, the dose rates at a source-to-surface distance (SSD) of 34 cm are 259 and 172 cGy min-1 at 6 mm and 2 cm depths, respectively, with an estimated uncertainty of ±5%. The per cent depth dose is approximately 56% at 2 cm depth for a beam at 34 cm SSD.
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U2 - 10.1088/0031-9155/52/10/007
DO - 10.1088/0031-9155/52/10/007
M3 - Article
C2 - 17473348
AN - SCOPUS:34248155254
SN - 0031-9155
VL - 52
JO - Physics in medicine and biology
JF - Physics in medicine and biology
IS - 10
M1 - 007
ER -