The small-animal radiation research platform (SARRP): Dosimetry of a focused lens system

Hua Deng, Christopher W. Kennedy, Elwood Armour, Erik Tryggestad, Eric Ford, Todd McNutt, Licai Jiang, John Wong

Research output: Contribution to journalArticle

Abstract

A small animal radiation platform equipped with on-board cone-beam CT and conformal irradiation capabilities is being constructed for translational research. To achieve highly localized dose delivery, an x-ray lens is used to focus the broad beam from a 225 kVp x-ray tube down to a beam with a full width half maximum (FWHM) of approximately 1.5 mm in the energy range 40-80 keV. Here, we report on the dosimetric characteristics of the focused beam from the x-ray lens subsystem for high-resolution dose delivery. Using the metric of the average dose within a 1.5 mm diameter area, the dose rates at a source-to-surface distance (SSD) of 34 cm are 259 and 172 cGy min-1 at 6 mm and 2 cm depths, respectively, with an estimated uncertainty of ±5%. The per cent depth dose is approximately 56% at 2 cm depth for a beam at 34 cm SSD.

Original languageEnglish (US)
Article number007
JournalPhysics in medicine and biology
Volume52
Issue number10
DOIs
StatePublished - May 21 2007

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ASJC Scopus subject areas

  • Radiological and Ultrasound Technology
  • Radiology Nuclear Medicine and imaging

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