De schildwachtklierprocedure: Standaardingreep bij de chirurgische behandeling van her mammacarcinoom

Translated title of the contribution: The sentinel node procedure: Standard intervention in the surgical treatment of breast cancer

S. Meijer, R. Pijpers, P. J. Borgstein, R. P. Bleichrodt, P. J. Van Diest

Research output: Contribution to journalArticle

Abstract

Axillary lymph node dissection may be avoided in the surgical treatment of breast cancer if the sentinel node appears to be free of metastatic tumour cells. The sentinel node concept has been validated in hundreds of patients, in whom this node has been localized successfully by dye-guided node mapping and (or) gamma-probe localization after injection of a radiopharmaceutical agent. The success rate of sentinel node localization depends on different factors, such as type, volume and injection site of the radiopharmacon, choice of the handheld gamma-probe, timing of the blue dye injection, and clinical stage of the disease. The combination of preoperative lymphoscintigraphy, intraoperative gamma-probe guidance and blue dye administration will increase the success rate of a sentinel node biopsy. Recent reports, from both Europe and the United States, appear to indicate that the sentinel node biopsy will soon be standard procedure in the surgical treatment of (T1-2) breast cancer. In the majority of breast cancer patients axillary lymph node dissection, a cause of much morbidity, may thus be avoided.

Translated title of the contributionThe sentinel node procedure: Standard intervention in the surgical treatment of breast cancer
Original languageDutch
Pages (from-to)2235-2237
Number of pages3
JournalNederlands Tijdschrift voor Geneeskunde
Volume142
Issue number41
StatePublished - Oct 10 1998
Externally publishedYes

ASJC Scopus subject areas

  • Medicine(all)

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  • Cite this

    Meijer, S., Pijpers, R., Borgstein, P. J., Bleichrodt, R. P., & Van Diest, P. J. (1998). De schildwachtklierprocedure: Standaardingreep bij de chirurgische behandeling van her mammacarcinoom. Nederlands Tijdschrift voor Geneeskunde, 142(41), 2235-2237.