Abstract
A second human calcitonin/calcitonin gene related peptide (hCT/CGRP) gene has been identified. This second hCT/CGRP gene has been shown to contain sequences highly homologous to exons 3, 5 (CGRP-encoding), and 6 of the first hCT/CGRP gene, but sequences closely related to exon 4 (CT-encoding) could not be demonstrated. Southern blot hybridization analysis of DNA from human-rodent somatic cell hybrids showed that the second hCT/CGRP gene is located in the q12-pter region of chromosome 11. The first hCT/CGRP gene has previously been assigned to the p13-p15 region of chromosome 11.
Original language | English (US) |
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Pages (from-to) | 259-263 |
Number of pages | 5 |
Journal | Human genetics |
Volume | 70 |
Issue number | 3 |
DOIs | |
State | Published - Jul 1985 |
ASJC Scopus subject areas
- Genetics
- Genetics(clinical)