The second generation HRRT - A multi-centre scanner performance investigation

Vesna Sossi, Hugo W A M De Jong, W. Craig Barker, Peter Bloomfield, Ziad Burbar, Marie Laure Camborde, Claude Comtat, Lars A. Eriksson, Sylvain Houle, David Keator, Christof Knöß, Roman Krais, Adriaan A. Lammertsma, Arman Rahmim, Mérence Sibomana, Mika Teräs, Christopher J. Thompson, Régine Trébossen, John Votaw, Matthew WalkerKlaus Wienhard, Dean Foster Wong

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

The high resolution research tomograph (HRRT) is one of the most complex existing Positron Emission Tomographs: it is the only human size scanner capable of decoding the depth of the γ-ray interaction in the crystal, using a lutetium LSO/LYSO phoswitch detector arrangement. In this study we determined basic scanner hardware characteristics, such as scanner data acquisition stability, and their variability across eleven centres. In addition a subset of the NEMA NU-2001 standards measurements was performed. We found (i) significant variability in the DOI decoding results between centres, (ii) a trend toward an increasing number of detected true coincident events as a function of elapsed time from scanner calibration likely due to a shifting energy spectrum, (iii) a count-rate dependent layer identification, (iv) scatter fraction ranging from ∼ 42% to 54% where the variability was partly related to the shifting of the energy spectrum, (v) sensitivity ranging from ∼ 5.5% to 6.5% across centres, (vi) resolution of ∼ (2.5mm)3, fairly consistent across centres, (vii) image quality which is very comparable to other scanners.

Original languageEnglish (US)
Title of host publicationIEEE Nuclear Science Symposium Conference Record
Pages2195-2199
Number of pages5
Volume4
DOIs
StatePublished - 2005
EventNuclear Science Symposium Conference Record, 2005 IEEE - , Puerto Rico
Duration: Oct 23 2005Oct 29 2005

Other

OtherNuclear Science Symposium Conference Record, 2005 IEEE
CountryPuerto Rico
Period10/23/0510/29/05

Fingerprint

Decoding
Lutetium
Positrons
Image quality
Data acquisition
Calibration
Detectors
Hardware
Crystals

Keywords

  • Depth of interaction
  • ECAT HRRT
  • High resolution research tomograph
  • Performance study
  • PET
  • Positron emission tomography
  • Resolution
  • Scatter fraction
  • Sensitivity
  • Stability

ASJC Scopus subject areas

  • Computer Vision and Pattern Recognition
  • Industrial and Manufacturing Engineering

Cite this

Sossi, V., De Jong, H. W. A. M., Barker, W. C., Bloomfield, P., Burbar, Z., Camborde, M. L., ... Wong, D. F. (2005). The second generation HRRT - A multi-centre scanner performance investigation. In IEEE Nuclear Science Symposium Conference Record (Vol. 4, pp. 2195-2199). [1596770] https://doi.org/10.1109/NSSMIC.2005.1596770

The second generation HRRT - A multi-centre scanner performance investigation. / Sossi, Vesna; De Jong, Hugo W A M; Barker, W. Craig; Bloomfield, Peter; Burbar, Ziad; Camborde, Marie Laure; Comtat, Claude; Eriksson, Lars A.; Houle, Sylvain; Keator, David; Knöß, Christof; Krais, Roman; Lammertsma, Adriaan A.; Rahmim, Arman; Sibomana, Mérence; Teräs, Mika; Thompson, Christopher J.; Trébossen, Régine; Votaw, John; Walker, Matthew; Wienhard, Klaus; Wong, Dean Foster.

IEEE Nuclear Science Symposium Conference Record. Vol. 4 2005. p. 2195-2199 1596770.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Sossi, V, De Jong, HWAM, Barker, WC, Bloomfield, P, Burbar, Z, Camborde, ML, Comtat, C, Eriksson, LA, Houle, S, Keator, D, Knöß, C, Krais, R, Lammertsma, AA, Rahmim, A, Sibomana, M, Teräs, M, Thompson, CJ, Trébossen, R, Votaw, J, Walker, M, Wienhard, K & Wong, DF 2005, The second generation HRRT - A multi-centre scanner performance investigation. in IEEE Nuclear Science Symposium Conference Record. vol. 4, 1596770, pp. 2195-2199, Nuclear Science Symposium Conference Record, 2005 IEEE, Puerto Rico, 10/23/05. https://doi.org/10.1109/NSSMIC.2005.1596770
Sossi V, De Jong HWAM, Barker WC, Bloomfield P, Burbar Z, Camborde ML et al. The second generation HRRT - A multi-centre scanner performance investigation. In IEEE Nuclear Science Symposium Conference Record. Vol. 4. 2005. p. 2195-2199. 1596770 https://doi.org/10.1109/NSSMIC.2005.1596770
Sossi, Vesna ; De Jong, Hugo W A M ; Barker, W. Craig ; Bloomfield, Peter ; Burbar, Ziad ; Camborde, Marie Laure ; Comtat, Claude ; Eriksson, Lars A. ; Houle, Sylvain ; Keator, David ; Knöß, Christof ; Krais, Roman ; Lammertsma, Adriaan A. ; Rahmim, Arman ; Sibomana, Mérence ; Teräs, Mika ; Thompson, Christopher J. ; Trébossen, Régine ; Votaw, John ; Walker, Matthew ; Wienhard, Klaus ; Wong, Dean Foster. / The second generation HRRT - A multi-centre scanner performance investigation. IEEE Nuclear Science Symposium Conference Record. Vol. 4 2005. pp. 2195-2199
@inproceedings{083a8b8a77af411ba9e6dcc82807450d,
title = "The second generation HRRT - A multi-centre scanner performance investigation",
abstract = "The high resolution research tomograph (HRRT) is one of the most complex existing Positron Emission Tomographs: it is the only human size scanner capable of decoding the depth of the γ-ray interaction in the crystal, using a lutetium LSO/LYSO phoswitch detector arrangement. In this study we determined basic scanner hardware characteristics, such as scanner data acquisition stability, and their variability across eleven centres. In addition a subset of the NEMA NU-2001 standards measurements was performed. We found (i) significant variability in the DOI decoding results between centres, (ii) a trend toward an increasing number of detected true coincident events as a function of elapsed time from scanner calibration likely due to a shifting energy spectrum, (iii) a count-rate dependent layer identification, (iv) scatter fraction ranging from ∼ 42{\%} to 54{\%} where the variability was partly related to the shifting of the energy spectrum, (v) sensitivity ranging from ∼ 5.5{\%} to 6.5{\%} across centres, (vi) resolution of ∼ (2.5mm)3, fairly consistent across centres, (vii) image quality which is very comparable to other scanners.",
keywords = "Depth of interaction, ECAT HRRT, High resolution research tomograph, Performance study, PET, Positron emission tomography, Resolution, Scatter fraction, Sensitivity, Stability",
author = "Vesna Sossi and {De Jong}, {Hugo W A M} and Barker, {W. Craig} and Peter Bloomfield and Ziad Burbar and Camborde, {Marie Laure} and Claude Comtat and Eriksson, {Lars A.} and Sylvain Houle and David Keator and Christof Kn{\"o}{\ss} and Roman Krais and Lammertsma, {Adriaan A.} and Arman Rahmim and M{\'e}rence Sibomana and Mika Ter{\"a}s and Thompson, {Christopher J.} and R{\'e}gine Tr{\'e}bossen and John Votaw and Matthew Walker and Klaus Wienhard and Wong, {Dean Foster}",
year = "2005",
doi = "10.1109/NSSMIC.2005.1596770",
language = "English (US)",
isbn = "0780392213",
volume = "4",
pages = "2195--2199",
booktitle = "IEEE Nuclear Science Symposium Conference Record",

}

TY - GEN

T1 - The second generation HRRT - A multi-centre scanner performance investigation

AU - Sossi, Vesna

AU - De Jong, Hugo W A M

AU - Barker, W. Craig

AU - Bloomfield, Peter

AU - Burbar, Ziad

AU - Camborde, Marie Laure

AU - Comtat, Claude

AU - Eriksson, Lars A.

AU - Houle, Sylvain

AU - Keator, David

AU - Knöß, Christof

AU - Krais, Roman

AU - Lammertsma, Adriaan A.

AU - Rahmim, Arman

AU - Sibomana, Mérence

AU - Teräs, Mika

AU - Thompson, Christopher J.

AU - Trébossen, Régine

AU - Votaw, John

AU - Walker, Matthew

AU - Wienhard, Klaus

AU - Wong, Dean Foster

PY - 2005

Y1 - 2005

N2 - The high resolution research tomograph (HRRT) is one of the most complex existing Positron Emission Tomographs: it is the only human size scanner capable of decoding the depth of the γ-ray interaction in the crystal, using a lutetium LSO/LYSO phoswitch detector arrangement. In this study we determined basic scanner hardware characteristics, such as scanner data acquisition stability, and their variability across eleven centres. In addition a subset of the NEMA NU-2001 standards measurements was performed. We found (i) significant variability in the DOI decoding results between centres, (ii) a trend toward an increasing number of detected true coincident events as a function of elapsed time from scanner calibration likely due to a shifting energy spectrum, (iii) a count-rate dependent layer identification, (iv) scatter fraction ranging from ∼ 42% to 54% where the variability was partly related to the shifting of the energy spectrum, (v) sensitivity ranging from ∼ 5.5% to 6.5% across centres, (vi) resolution of ∼ (2.5mm)3, fairly consistent across centres, (vii) image quality which is very comparable to other scanners.

AB - The high resolution research tomograph (HRRT) is one of the most complex existing Positron Emission Tomographs: it is the only human size scanner capable of decoding the depth of the γ-ray interaction in the crystal, using a lutetium LSO/LYSO phoswitch detector arrangement. In this study we determined basic scanner hardware characteristics, such as scanner data acquisition stability, and their variability across eleven centres. In addition a subset of the NEMA NU-2001 standards measurements was performed. We found (i) significant variability in the DOI decoding results between centres, (ii) a trend toward an increasing number of detected true coincident events as a function of elapsed time from scanner calibration likely due to a shifting energy spectrum, (iii) a count-rate dependent layer identification, (iv) scatter fraction ranging from ∼ 42% to 54% where the variability was partly related to the shifting of the energy spectrum, (v) sensitivity ranging from ∼ 5.5% to 6.5% across centres, (vi) resolution of ∼ (2.5mm)3, fairly consistent across centres, (vii) image quality which is very comparable to other scanners.

KW - Depth of interaction

KW - ECAT HRRT

KW - High resolution research tomograph

KW - Performance study

KW - PET

KW - Positron emission tomography

KW - Resolution

KW - Scatter fraction

KW - Sensitivity

KW - Stability

UR - http://www.scopus.com/inward/record.url?scp=33846562611&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=33846562611&partnerID=8YFLogxK

U2 - 10.1109/NSSMIC.2005.1596770

DO - 10.1109/NSSMIC.2005.1596770

M3 - Conference contribution

AN - SCOPUS:33846562611

SN - 0780392213

SN - 9780780392212

VL - 4

SP - 2195

EP - 2199

BT - IEEE Nuclear Science Symposium Conference Record

ER -