The search for ESR1 mutations in breast cancer

Steffi Oesterreich, Nancy E. Davidson

Research output: Contribution to journalArticlepeer-review


Two new studies report the identification of activating ESR1 gene mutations in aromatase inhibitor-resistant metastatic breast cancers. This insight into therapeutic resistance suggests new approaches that may be useful in the management of endocrine-resistant breast cancer.

Original languageEnglish (US)
Pages (from-to)1415-1416
Number of pages2
JournalNature genetics
Issue number12
StatePublished - Dec 2013
Externally publishedYes

ASJC Scopus subject areas

  • Genetics


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