The schizophrenia syndrome. Examples of biological tools for subclassification

R. J. Wyatt; S. G. Potkin; J. E. Kleinman; D. R. Weinberger; D. J. Luchins; D. V. Jeste

doi:10.1097/00005053-198102000-00005

The schizophrenia syndrome. Examples of biological tools for subclassification

R. J. Wyatt, S. G. Potkin, J. E. Kleinman, D. R. Weinberger, D. J. Luchins, D. V. Jeste

Research output: Contribution to journal › Review article

Abstract

Six biological variables - platelet monoamine oxidase activity, urine phenylethylamine concentration, brain norepinephrine concentration, abnormalities on computerized tomography, lateralization asymmetries, and the presence or absence of tardive dyskinesia - are used to discriminate possible biological groups of schizophrenic patients. All variables successfully subclassify patients, some into divisions consistent with phenomenological, psychosocial, or biochemical descriptions or hypotheses of schizophrenia. None of the measures, however, has sufficiently stood the test of time to be of clinical utility.

Original language	English (US)
Pages (from-to)	100-112
Number of pages	13
Journal	Unknown Journal
Volume	169
Issue number	2
DOIs	https://doi.org/10.1097/00005053-198102000-00005
State	Published - Jan 1 1981
Externally published	Yes

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ASJC Scopus subject areas

Psychiatry and Mental health

Cite this

Wyatt, R. J., Potkin, S. G., Kleinman, J. E., Weinberger, D. R., Luchins, D. J., & Jeste, D. V. (1981). The schizophrenia syndrome. Examples of biological tools for subclassification. Unknown Journal, 169(2), 100-112. https://doi.org/10.1097/00005053-198102000-00005

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10.1097/00005053-198102000-00005