Abstract
Six biological variables - platelet monoamine oxidase activity, urine phenylethylamine concentration, brain norepinephrine concentration, abnormalities on computerized tomography, lateralization asymmetries, and the presence or absence of tardive dyskinesia - are used to discriminate possible biological groups of schizophrenic patients. All variables successfully subclassify patients, some into divisions consistent with phenomenological, psychosocial, or biochemical descriptions or hypotheses of schizophrenia. None of the measures, however, has sufficiently stood the test of time to be of clinical utility.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 100-112 |
| Number of pages | 13 |
| Journal | Journal of Nervous and Mental Disease |
| Volume | 169 |
| Issue number | 2 |
| State | Published - 1981 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Psychiatry and Mental health
Cite this
The schizophrenia syndrome. Examples of biological tools for subclassification. / Wyatt, R. J.; Potkin, S. G.; Kleinman, Joel; Weinberger, Daniel; Luchins, D. J.; Jeste, D. V.
In: Journal of Nervous and Mental Disease, Vol. 169, No. 2, 1981, p. 100-112.Research output: Contribution to journal › Review article
}
TY - JOUR
T1 - The schizophrenia syndrome. Examples of biological tools for subclassification
AU - Wyatt, R. J.
AU - Potkin, S. G.
AU - Kleinman, Joel
AU - Weinberger, Daniel
AU - Luchins, D. J.
AU - Jeste, D. V.
PY - 1981
Y1 - 1981
N2 - Six biological variables - platelet monoamine oxidase activity, urine phenylethylamine concentration, brain norepinephrine concentration, abnormalities on computerized tomography, lateralization asymmetries, and the presence or absence of tardive dyskinesia - are used to discriminate possible biological groups of schizophrenic patients. All variables successfully subclassify patients, some into divisions consistent with phenomenological, psychosocial, or biochemical descriptions or hypotheses of schizophrenia. None of the measures, however, has sufficiently stood the test of time to be of clinical utility.
AB - Six biological variables - platelet monoamine oxidase activity, urine phenylethylamine concentration, brain norepinephrine concentration, abnormalities on computerized tomography, lateralization asymmetries, and the presence or absence of tardive dyskinesia - are used to discriminate possible biological groups of schizophrenic patients. All variables successfully subclassify patients, some into divisions consistent with phenomenological, psychosocial, or biochemical descriptions or hypotheses of schizophrenia. None of the measures, however, has sufficiently stood the test of time to be of clinical utility.
UR - http://www.scopus.com/inward/record.url?scp=0019778257&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0019778257&partnerID=8YFLogxK
M3 - Review article
VL - 169
SP - 100
EP - 112
JO - Journal of Nervous and Mental Disease
JF - Journal of Nervous and Mental Disease
SN - 0022-3018
IS - 2
ER -