TY - JOUR
T1 - The schizophrenia syndrome. Examples of biological tools for subclassification
AU - Wyatt, R. J.
AU - Potkin, S. G.
AU - Kleinman, J. E.
AU - Weinberger, D. R.
AU - Luchins, D. J.
AU - Jeste, D. V.
PY - 1981/1/1
Y1 - 1981/1/1
N2 - Six biological variables - platelet monoamine oxidase activity, urine phenylethylamine concentration, brain norepinephrine concentration, abnormalities on computerized tomography, lateralization asymmetries, and the presence or absence of tardive dyskinesia - are used to discriminate possible biological groups of schizophrenic patients. All variables successfully subclassify patients, some into divisions consistent with phenomenological, psychosocial, or biochemical descriptions or hypotheses of schizophrenia. None of the measures, however, has sufficiently stood the test of time to be of clinical utility.
AB - Six biological variables - platelet monoamine oxidase activity, urine phenylethylamine concentration, brain norepinephrine concentration, abnormalities on computerized tomography, lateralization asymmetries, and the presence or absence of tardive dyskinesia - are used to discriminate possible biological groups of schizophrenic patients. All variables successfully subclassify patients, some into divisions consistent with phenomenological, psychosocial, or biochemical descriptions or hypotheses of schizophrenia. None of the measures, however, has sufficiently stood the test of time to be of clinical utility.
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U2 - 10.1097/00005053-198102000-00005
DO - 10.1097/00005053-198102000-00005
M3 - Review article
C2 - 7009783
AN - SCOPUS:0019778257
VL - 169
SP - 100
EP - 112
JO - Advances in Water Resources
JF - Advances in Water Resources
SN - 0309-1708
IS - 2
ER -