Abstract
A Chinese β+-thalassemia gene in a new haplotype was chosen for cloning and sequencing. The mutation identified was an A-G transition at position-29 in the TATA box of the β-globin gene. This mutation has not been seen previously in Chinese but has been documented in American blacks on a different chromosomal background. This observation provides further evidence for independent origins of the same mutation in distinct ethnic groups.
Original language | English (US) |
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Pages (from-to) | 162-164 |
Number of pages | 3 |
Journal | Human genetics |
Volume | 74 |
Issue number | 2 |
DOIs | |
State | Published - Oct 1 1986 |
ASJC Scopus subject areas
- Genetics
- Genetics(clinical)