The safety of multi-dose vials in allergy immunotherapy

Sandra Y Lin, P. Chase Lay, Larry F. Hughes, Richard Bass

Research output: Contribution to journalArticle

Abstract

Objective: To prospectively evaluate the risks of vial contamination after routine clinical use of multiple-dose vials for immunotherapy. Study Design: Prospective observational study of immunotherapy vial cultures from June 2007 to January 2008. Setting: Tertiary care outpatient otolaryngology clinic. Results: Over an 8-month period, 136 consecutive vials were cultured for aerobic and anaerobic bacteria at the 3-month expiration date after regular use in an outpatient allergy clinic and dispensation of multiple doses of injection immunotherapy from each vial. All vials had negative cultures. Conclusion: Immunotherapy vials are at low risk to undergo contamination in routine use. Important factors include aseptic technique, bacteriostatic agents, and expiration dating.

Original languageEnglish (US)
Pages (from-to)195-197
Number of pages3
JournalOtolaryngology - Head and Neck Surgery
Volume139
Issue number2
DOIs
StatePublished - Aug 2008

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Immunotherapy
Hypersensitivity
Safety
Ambulatory Care Facilities
Aerobic Bacteria
Anaerobic Bacteria
Otolaryngology
Tertiary Healthcare
Observational Studies
Prospective Studies
Injections

ASJC Scopus subject areas

  • Otorhinolaryngology

Cite this

The safety of multi-dose vials in allergy immunotherapy. / Lin, Sandra Y; Lay, P. Chase; Hughes, Larry F.; Bass, Richard.

In: Otolaryngology - Head and Neck Surgery, Vol. 139, No. 2, 08.2008, p. 195-197.

Research output: Contribution to journalArticle

Lin, Sandra Y ; Lay, P. Chase ; Hughes, Larry F. ; Bass, Richard. / The safety of multi-dose vials in allergy immunotherapy. In: Otolaryngology - Head and Neck Surgery. 2008 ; Vol. 139, No. 2. pp. 195-197.
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