The safety of multi-dose vials in allergy immunotherapy

Sandra Y. Lin; P. Chase Lay; Larry F. Hughes; Richard Bass

doi:10.1016/j.otohns.2008.05.013

The safety of multi-dose vials in allergy immunotherapy

Sandra Y. Lin, P. Chase Lay, Larry F. Hughes, Richard Bass

Research output: Contribution to journal › Article › peer-review

11 Scopus citations

Abstract

Objective: To prospectively evaluate the risks of vial contamination after routine clinical use of multiple-dose vials for immunotherapy. Study Design: Prospective observational study of immunotherapy vial cultures from June 2007 to January 2008. Setting: Tertiary care outpatient otolaryngology clinic. Results: Over an 8-month period, 136 consecutive vials were cultured for aerobic and anaerobic bacteria at the 3-month expiration date after regular use in an outpatient allergy clinic and dispensation of multiple doses of injection immunotherapy from each vial. All vials had negative cultures. Conclusion: Immunotherapy vials are at low risk to undergo contamination in routine use. Important factors include aseptic technique, bacteriostatic agents, and expiration dating.

Original language	English (US)
Pages (from-to)	195-197
Number of pages	3
Journal	Otolaryngology - Head and Neck Surgery
Volume	139
Issue number	2
DOIs	https://doi.org/10.1016/j.otohns.2008.05.013
State	Published - Aug 2008
Externally published	Yes

ASJC Scopus subject areas

Surgery
Otorhinolaryngology

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10.1016/j.otohns.2008.05.013

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title = "The safety of multi-dose vials in allergy immunotherapy",

abstract = "Objective: To prospectively evaluate the risks of vial contamination after routine clinical use of multiple-dose vials for immunotherapy. Study Design: Prospective observational study of immunotherapy vial cultures from June 2007 to January 2008. Setting: Tertiary care outpatient otolaryngology clinic. Results: Over an 8-month period, 136 consecutive vials were cultured for aerobic and anaerobic bacteria at the 3-month expiration date after regular use in an outpatient allergy clinic and dispensation of multiple doses of injection immunotherapy from each vial. All vials had negative cultures. Conclusion: Immunotherapy vials are at low risk to undergo contamination in routine use. Important factors include aseptic technique, bacteriostatic agents, and expiration dating.",

author = "Lin, {Sandra Y.} and Lay, {P. Chase} and Hughes, {Larry F.} and Richard Bass",

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AB - Objective: To prospectively evaluate the risks of vial contamination after routine clinical use of multiple-dose vials for immunotherapy. Study Design: Prospective observational study of immunotherapy vial cultures from June 2007 to January 2008. Setting: Tertiary care outpatient otolaryngology clinic. Results: Over an 8-month period, 136 consecutive vials were cultured for aerobic and anaerobic bacteria at the 3-month expiration date after regular use in an outpatient allergy clinic and dispensation of multiple doses of injection immunotherapy from each vial. All vials had negative cultures. Conclusion: Immunotherapy vials are at low risk to undergo contamination in routine use. Important factors include aseptic technique, bacteriostatic agents, and expiration dating.

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The safety of multi-dose vials in allergy immunotherapy

Abstract

ASJC Scopus subject areas

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