The safety and efficacy of chloral hydrate sedation for pediatric ophthalmic procedures: A retrospective review

Michelle E. Wilson, Mohammed Karaoui, Leyla Al Djasim, Deepak P. Edward, Mohammad Al Shamrani, David S. Friedman

Research output: Contribution to journalArticle

Abstract

Purpose: To determine the safety and efficacy of high-dose oral chloral hydrate for pediatric ophthalmic procedures. Methods: This study is a retrospective review of a quality audit of pediatric sedation for ophthalmic evaluation and imaging performed at King Khaled Eye Specialist Hospital between January 1 and December 31, 2011, in children aged 1 month to 6 years. Results: Three hundred fifty-eight of 380 (94.2%) sedation procedures were successful after a single dose of chloral hydrate, with 356 of 380 (93.7%) children sedated within 45 minutes of the first dose. The total success rate of the sedation procedure increased to 97.9% (372 of 380) when a second dose was administered. Children adequately sedated after a single dose of chloral hydrate were on average younger and weighed less than children who required additional doses. No major adverse events were documented. Conclusions: The use of chloral hydrate sedation for ophthalmic evaluation and imaging was safe and effective in this patient population with a high rate of procedure completion.

Original languageEnglish (US)
Pages (from-to)154-159
Number of pages6
JournalJournal of pediatric ophthalmology and strabismus
Volume51
Issue number3
DOIs
StatePublished - 2014

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ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Ophthalmology

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