The Role of Viral Co-Infection in HIV-Associated Non-AIDS-Related Cancers

David J. Riedel, Lydia S. Tang, Anne F. Rositch

Research output: Contribution to journalReview articlepeer-review

Abstract

HIV-infected individuals are at increased risk for most types of cancer, including those typically classified as non-AIDS-defining cancers (NADCs). This increased risk is likely multifactorial, but a prominent risk factor for the increased rate of some cancers is co-infection with oncogenic viruses. Anal cancer, hepatocellular carcinoma, and Hodgkin lymphoma are three of the most common NADCs, and they are associated with co-infection with human papillomavirus, hepatitis B and C, and Epstein Barr virus, respectively. This review will examine the epidemiology, pathogenesis, and future trends around these virally associated NADCs frequently found in HIV-infected individuals.

Original languageEnglish (US)
Pages (from-to)362-372
Number of pages11
JournalCurrent HIV/AIDS reports
Volume12
Issue number3
DOIs
StatePublished - Sep 10 2015

Keywords

  • AIDS
  • Anal cancer
  • HIV
  • Hepatocellular carcinoma
  • Hodgkin lymphoma
  • Non-AIDS-defining cancer

ASJC Scopus subject areas

  • Virology
  • Infectious Diseases

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