The role of the microbiology laboratory in antimicrobial stewardship programs

Edina Avdic, Karen C. Carroll

Research output: Contribution to journalReview articlepeer-review

Abstract

One of the impediments to the success of antimicrobial stewardship is the lack of availability of rapid and sensitive laboratory tests. The last decade has seen an explosion in new technologies that permit, in less than 4hours, the identification of organisms and their resistance markers. In addition, the use of biomarkers has been explored in algorithms to distinguish infections that require antimicrobial agents. Clinical microbiology laboratories also contribute to the success of stewardship programs through compilation of aggregate antimicrobial susceptibility data. This article reviews rapid diagnostics, the use of biomarkers, and antibiogram development to antimicrobial stewardship activities and the subsequent impact on patient outcomes.

Original languageEnglish (US)
Pages (from-to)215-235
Number of pages21
JournalInfectious disease clinics of North America
Volume28
Issue number2
DOIs
StatePublished - Jun 2014

Keywords

  • Antibiogram
  • Antimicrobial stewardship
  • Microbiology laboratory
  • Procalcitonin
  • Rapid diagnostics

ASJC Scopus subject areas

  • Microbiology (medical)
  • Infectious Diseases

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