TY - JOUR
T1 - The role of surgical intervention in non-Hodgkin's lymphoma of the colon and rectum
AU - Cai, Steven
AU - Cannizzo, Francis
AU - Bullard Dunn, Kelli M.
AU - Gibbs, John F.
AU - Czuczman, Myron
AU - Rajput, Ashwani
N1 - Copyright:
Copyright 2008 Elsevier B.V., All rights reserved.
PY - 2007/3
Y1 - 2007/3
N2 - Background: Gastrointestinal involvement of non-Hodgkin's lymphoma (NHL), although rare, may require surgical intervention. The purpose of the current study was to determine the incidence, presentation, and management of patients with NHL of the colon or rectum. Methods: Demographic data, signs, symptoms, disease stage, and treatment of patients with a primary gastrointestinal lymphoma treated between 1973 and 2005 were identified. Results: Forty-three of 244 gastrointestinal lymphoma patients (18%) had colon or rectal involvement. Most common symptoms on presentation were pain (49%), hematochezia (49%), change in bowel habits (23%), and weight loss (19%). Most common site of involvement was the ileocecum. Twenty-six patients (60%) required surgery. The majority (56%) had urgent or emergent operations. Conclusions: Colorectal involvement by NHL occurred in 18% of patients with gastrointestinal lymphoma. Surgery was required for pain, obstruction, and/or bleeding. Physicians caring for patients must be aware of the potential need for surgery in treating this patient population.
AB - Background: Gastrointestinal involvement of non-Hodgkin's lymphoma (NHL), although rare, may require surgical intervention. The purpose of the current study was to determine the incidence, presentation, and management of patients with NHL of the colon or rectum. Methods: Demographic data, signs, symptoms, disease stage, and treatment of patients with a primary gastrointestinal lymphoma treated between 1973 and 2005 were identified. Results: Forty-three of 244 gastrointestinal lymphoma patients (18%) had colon or rectal involvement. Most common symptoms on presentation were pain (49%), hematochezia (49%), change in bowel habits (23%), and weight loss (19%). Most common site of involvement was the ileocecum. Twenty-six patients (60%) required surgery. The majority (56%) had urgent or emergent operations. Conclusions: Colorectal involvement by NHL occurred in 18% of patients with gastrointestinal lymphoma. Surgery was required for pain, obstruction, and/or bleeding. Physicians caring for patients must be aware of the potential need for surgery in treating this patient population.
KW - Colon
KW - Non-Hodgkin's lymphoma
KW - Rectum
KW - Surgery
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U2 - 10.1016/j.amjsurg.2006.12.007
DO - 10.1016/j.amjsurg.2006.12.007
M3 - Article
C2 - 17320545
AN - SCOPUS:33847084683
VL - 193
SP - 409
EP - 412
JO - American Journal of Surgery
JF - American Journal of Surgery
SN - 0002-9610
IS - 3
ER -