The role of miRNAs in endometrial cancer

Diamantina Vasilatou, Vasileios D. Sioulas, Vasiliki Pappa, Sotirios G. Papageorgiou, Nikolaos F. Vlahos

    Research output: Contribution to journalArticle

    Abstract

    miRNAs are small noncoding RNAs that regulate gene expression at the post-transcriptional level. Since their discovery, miRNAs have been associated with every cell function including malignant transformation and metastasis. Endometrial cancer is the most common gynecologic malignancy. However, improvement should be made in interobserver agreement on histological typing and individualized therapeutic approaches. This article summarizes the role of miRNAs in endometrial cancer pathogenesis and treatment.

    Original languageEnglish (US)
    Pages (from-to)951-959
    Number of pages9
    JournalEpigenomics
    Volume7
    Issue number6
    DOIs
    StatePublished - Sep 2015

    Keywords

    • endometrial cancer
    • metastasis
    • miR-200
    • miRNAs

    ASJC Scopus subject areas

    • Genetics
    • Cancer Research

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  • Cite this

    Vasilatou, D., Sioulas, V. D., Pappa, V., Papageorgiou, S. G., & Vlahos, N. F. (2015). The role of miRNAs in endometrial cancer. Epigenomics, 7(6), 951-959. https://doi.org/10.2217/epi.15.41