The role of inflammatory mediators in allergic rhinitis

R. Naclerio; D. Proud; S. Peters; A. K. Sobotka; L. Lichtenstein; P. Norman

The role of inflammatory mediators in allergic rhinitis

R. Naclerio, D. Proud, S. Peters, A. K. Sobotka, L. Lichtenstein, P. Norman

School of Medicine

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

We describe a nasal challenge model for allergic rhinitis. This model demonstrates the presence of inflammatory mediators during both the early and the late reactions following exposure to specific allergens. The mediators measured include histamine, TAME-esterase, kinin, leukotriene C₄, and prostaglandin D₂. A discussion of their role in the pathophysiology of allergic rhinitis is presented.

Original language	English (US)
Pages (from-to)	206-212
Number of pages	7
Journal	Ear, Nose and Throat Journal
Volume	65
Issue number	5
State	Published - 1986

ASJC Scopus subject areas

Otorhinolaryngology

Cite this

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title = "The role of inflammatory mediators in allergic rhinitis",

abstract = "We describe a nasal challenge model for allergic rhinitis. This model demonstrates the presence of inflammatory mediators during both the early and the late reactions following exposure to specific allergens. The mediators measured include histamine, TAME-esterase, kinin, leukotriene C4, and prostaglandin D2. A discussion of their role in the pathophysiology of allergic rhinitis is presented.",

author = "R. Naclerio and D. Proud and S. Peters and Sobotka, {A. K.} and L. Lichtenstein and P. Norman",

year = "1986",

language = "English (US)",

volume = "65",

pages = "206--212",

journal = "Ear, Nose and Throat Journal",

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publisher = "Medquest Communications LLC",

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TY - JOUR

T1 - The role of inflammatory mediators in allergic rhinitis

AU - Naclerio, R.

AU - Proud, D.

AU - Peters, S.

AU - Sobotka, A. K.

AU - Lichtenstein, L.

AU - Norman, P.

PY - 1986

Y1 - 1986

N2 - We describe a nasal challenge model for allergic rhinitis. This model demonstrates the presence of inflammatory mediators during both the early and the late reactions following exposure to specific allergens. The mediators measured include histamine, TAME-esterase, kinin, leukotriene C4, and prostaglandin D2. A discussion of their role in the pathophysiology of allergic rhinitis is presented.

AB - We describe a nasal challenge model for allergic rhinitis. This model demonstrates the presence of inflammatory mediators during both the early and the late reactions following exposure to specific allergens. The mediators measured include histamine, TAME-esterase, kinin, leukotriene C4, and prostaglandin D2. A discussion of their role in the pathophysiology of allergic rhinitis is presented.

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M3 - Article

C2 - 3459645

AN - SCOPUS:0022587365

SN - 0145-5613

VL - 65

SP - 206

EP - 212

JO - Ear, Nose and Throat Journal

JF - Ear, Nose and Throat Journal

IS - 5

ER -

The role of inflammatory mediators in allergic rhinitis

Abstract

ASJC Scopus subject areas

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