The role of inflammatory mediators in allergic rhinitis

R. Naclerio; D. Proud; S. Peters; A. K. Sobotka; L. Lichtenstein; P. Norman

The role of inflammatory mediators in allergic rhinitis

R. Naclerio, D. Proud, S. Peters, A. K. Sobotka, L. Lichtenstein, P. Norman

School of Medicine

Research output: Contribution to journal › Article › peer-review

Abstract

We describe a nasal challenge model for allergic rhinitis. This model demonstrates the presence of inflammatory mediators during both the early and the late reactions following exposure to specific allergens. The mediators measured include histamine, TAME-esterase, kinin, leukotriene C₄, and prostaglandin D₂. A discussion of their role in the pathophysiology of allergic rhinitis is presented.

Original language	English (US)
Pages (from-to)	206-212
Number of pages	7
Journal	Ear, Nose and Throat Journal
Volume	65
Issue number	5
State	Published - 1986

ASJC Scopus subject areas

Otorhinolaryngology

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title = "The role of inflammatory mediators in allergic rhinitis",

abstract = "We describe a nasal challenge model for allergic rhinitis. This model demonstrates the presence of inflammatory mediators during both the early and the late reactions following exposure to specific allergens. The mediators measured include histamine, TAME-esterase, kinin, leukotriene C4, and prostaglandin D2. A discussion of their role in the pathophysiology of allergic rhinitis is presented.",

author = "R. Naclerio and D. Proud and S. Peters and Sobotka, {A. K.} and L. Lichtenstein and P. Norman",

year = "1986",

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AU - Proud, D.

AU - Peters, S.

AU - Sobotka, A. K.

AU - Lichtenstein, L.

AU - Norman, P.

PY - 1986

Y1 - 1986

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AB - We describe a nasal challenge model for allergic rhinitis. This model demonstrates the presence of inflammatory mediators during both the early and the late reactions following exposure to specific allergens. The mediators measured include histamine, TAME-esterase, kinin, leukotriene C4, and prostaglandin D2. A discussion of their role in the pathophysiology of allergic rhinitis is presented.

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M3 - Article

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AN - SCOPUS:0022587365

VL - 65

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JO - Ear, Nose and Throat Journal

JF - Ear, Nose and Throat Journal

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The role of inflammatory mediators in allergic rhinitis

Abstract

ASJC Scopus subject areas

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