The role of inflammation in bronchial stump healing

R. N. Scott, R. P. Faraci, D. G. Goodman, T. C. Militano, G. W. Geelhoed, P. B. Chretien

Research output: Contribution to journalArticle

Abstract

The roles of inflammatory response and closure technique in the development of bronchopleural fistula were evaluated. Canine bronchial stumps closed with 3-0 silk and studied 14 days later were characterized by a dense inflammatory infiltrate. Stumps closed with 3-0 chromic catgut suture showed a moderate inflammatory response with disintegration of suture material. However, stumps closed with the automatic stapling device (TA 30) showed the best healing and a minimal degree of inflammation. These findings correlated well with leakage pressures. The average leakage pressure for the silk closed stumps was 139.44 mm Hg ± 78.9 SD. This was significantly lower (P <0.02) than the average leakage pressure for staple closed stumps (251.25 mm Hg ± 82.9 SD). It is concluded that the minimal amount of inflammation following staple closure will be associated with improved bronchial stump healing and a lower incidence of bronchopleural fistula.

Original languageEnglish (US)
Pages (from-to)381-385
Number of pages5
JournalAnnals of Surgery
Volume181
Issue number4
StatePublished - 1975
Externally publishedYes

Fingerprint

Silk
Inflammation
Pressure
Sutures
Fistula
Catgut
Canidae
Equipment and Supplies
Incidence

ASJC Scopus subject areas

  • Surgery

Cite this

Scott, R. N., Faraci, R. P., Goodman, D. G., Militano, T. C., Geelhoed, G. W., & Chretien, P. B. (1975). The role of inflammation in bronchial stump healing. Annals of Surgery, 181(4), 381-385.

The role of inflammation in bronchial stump healing. / Scott, R. N.; Faraci, R. P.; Goodman, D. G.; Militano, T. C.; Geelhoed, G. W.; Chretien, P. B.

In: Annals of Surgery, Vol. 181, No. 4, 1975, p. 381-385.

Research output: Contribution to journalArticle

Scott, RN, Faraci, RP, Goodman, DG, Militano, TC, Geelhoed, GW & Chretien, PB 1975, 'The role of inflammation in bronchial stump healing', Annals of Surgery, vol. 181, no. 4, pp. 381-385.
Scott RN, Faraci RP, Goodman DG, Militano TC, Geelhoed GW, Chretien PB. The role of inflammation in bronchial stump healing. Annals of Surgery. 1975;181(4):381-385.
Scott, R. N. ; Faraci, R. P. ; Goodman, D. G. ; Militano, T. C. ; Geelhoed, G. W. ; Chretien, P. B. / The role of inflammation in bronchial stump healing. In: Annals of Surgery. 1975 ; Vol. 181, No. 4. pp. 381-385.
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