The role of free prostate-specific antigen in prostate cancer detection

Misop Han; Steven R. Potter; Alan W. Partin

doi:10.1007/s11934-000-0039-8

The role of free prostate-specific antigen in prostate cancer detection

Misop Han, Steven R. Potter, Alan W. Partin

School of Medicine

Research output: Contribution to journal › Article › peer-review

8 Scopus citations

Abstract

Prostate-specific antigen (PSA) is the most important serum tumor marker for prostate cancer detection. Free PSA is one of the many molecular forms of PSA that have been identified. Percent free PSA improves the specificity (elimination of unnecessary biopsies) for prostate cancer detection in men with nonsuspicious digital prostate examination and total serum PSA ranges between 4 and 10 ng/ mL. Further study is necessary to determine the optimal clinical utility of percent free PSA in men with a total serum PSA level of less than 4 ng/mL. In addition, the level of free PSA may be affected by many factors, including age, prostate volume, prostate manipulation, sample handling, and type of assay used.

Original language	English (US)
Pages (from-to)	78-82
Number of pages	5
Journal	Current urology reports
Volume	1
Issue number	1
DOIs	https://doi.org/10.1007/s11934-000-0039-8
State	Published - Mar 2000

Keywords

Human Glandular Kallikrein
Prostate Cancer
Prostate Cancer Detection
Prostate Manipulation
Prostate Volume

ASJC Scopus subject areas

Urology

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10.1007/s11934-000-0039-8

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title = "The role of free prostate-specific antigen in prostate cancer detection",

abstract = "Prostate-specific antigen (PSA) is the most important serum tumor marker for prostate cancer detection. Free PSA is one of the many molecular forms of PSA that have been identified. Percent free PSA improves the specificity (elimination of unnecessary biopsies) for prostate cancer detection in men with nonsuspicious digital prostate examination and total serum PSA ranges between 4 and 10 ng/ mL. Further study is necessary to determine the optimal clinical utility of percent free PSA in men with a total serum PSA level of less than 4 ng/mL. In addition, the level of free PSA may be affected by many factors, including age, prostate volume, prostate manipulation, sample handling, and type of assay used.",

keywords = "Human Glandular Kallikrein, Prostate Cancer, Prostate Cancer Detection, Prostate Manipulation, Prostate Volume",

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AU - Potter, Steven R.

AU - Partin, Alan W.

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AB - Prostate-specific antigen (PSA) is the most important serum tumor marker for prostate cancer detection. Free PSA is one of the many molecular forms of PSA that have been identified. Percent free PSA improves the specificity (elimination of unnecessary biopsies) for prostate cancer detection in men with nonsuspicious digital prostate examination and total serum PSA ranges between 4 and 10 ng/ mL. Further study is necessary to determine the optimal clinical utility of percent free PSA in men with a total serum PSA level of less than 4 ng/mL. In addition, the level of free PSA may be affected by many factors, including age, prostate volume, prostate manipulation, sample handling, and type of assay used.

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KW - Prostate Cancer Detection

KW - Prostate Manipulation

KW - Prostate Volume

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The role of free prostate-specific antigen in prostate cancer detection

Abstract

Keywords

ASJC Scopus subject areas

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