The role of endoscopic third ventriculostomy in the treatment of hydrocephalus Clinical article

Timothy W. Vogel, Biji Bahuleyan, Shenandoah Robinson, Alan R. Cohen

Research output: Contribution to journalArticlepeer-review

Abstract

Object. Hydrocephalus remains a major public health problem. Conventional treatment has relied on extracranial shunting of CSF to another systemic site, but this approach is associated with a high rate of complications. Endoscopic third ventriculostomy (ETV) is a novel treatment for select forms of hydrocephalus that can eliminate the need for implantation of a lifelong ventricular shunt system. However, the indications for ETV are contested and its long-term effectiveness is not well established. Methods. The authors selected 100 consecutive patients who underwent ETV for hydrocephalus beginning in 1994. Patients were enrolled and treated at a single institution by a single surgeon. The primary outcome was success of ETV, with success defined as no need for subsequent surgery for hydrocephalus. Results. Ninety-five patients satisfied the inclusion criteria. The mean follow-up period was 5.1 years (median 4.7 years) with follow-up data available for as long as 17 years. Patients commonly presented with headache (85%), ataxia (34%), emesis (29%), and changes in vision (27%). The success rate for ETV was 75%. Twenty-one patients (22%) in the series had malfunctioning shunts preoperatively and 13 (62%) were successfully treated with ETV. Preoperative inferior bowing of the third ventricle floor on MRI was significantly associated with ETV success (p < 0.05). Conclusions. Endoscopic third ventriculostomy is an effective and durable treatment for select patients with hydrocephalus. When successful, the procedure eliminates the lifelong complications associated with implanted ventricular shunts.

Original languageEnglish (US)
Pages (from-to)54-61
Number of pages8
JournalJournal of Neurosurgery: Pediatrics
Volume12
Issue number1
DOIs
StatePublished - Jul 1 2013
Externally publishedYes

Keywords

  • Endoscopic third ventriculostomy
  • Endoscopy
  • Hydrocephalus
  • Minimally invasive surgery
  • Neuroendoscopy

ASJC Scopus subject areas

  • Surgery
  • Pediatrics, Perinatology, and Child Health
  • Clinical Neurology

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