The Role of Echinocandins in Candida Biofilm-Related Vascular Catheter Infections: In Vitro and in Vivo Model Systems

Mahmoud Ghannoum, Emmanuel Roilides, Aspasia Katragkou, Vidmantas Petraitis, Thomas J. Walsh

Research output: Contribution to journalArticle

Abstract

Candida biofilm-associated infections of central venous catheters are a challenging therapeutic problem. Recent in vitro and in vivo studies of the structure, formation, pathogenesis, and treatment establish a rationale for new approaches to management of these tenacious infections.

Original languageEnglish (US)
Pages (from-to)S618-S621
JournalClinical Infectious Diseases
Volume61
DOIs
StatePublished - Dec 1 2015
Externally publishedYes

Fingerprint

Echinocandins
Catheter-Related Infections
Vascular Access Devices
Biofilms
Candida
Central Venous Catheters
Infection
In Vitro Techniques
Therapeutics

Keywords

  • anidulafungin
  • biofilm
  • caspofungin
  • echinocandin
  • micafungin

ASJC Scopus subject areas

  • Infectious Diseases
  • Microbiology (medical)

Cite this

The Role of Echinocandins in Candida Biofilm-Related Vascular Catheter Infections : In Vitro and in Vivo Model Systems. / Ghannoum, Mahmoud; Roilides, Emmanuel; Katragkou, Aspasia; Petraitis, Vidmantas; Walsh, Thomas J.

In: Clinical Infectious Diseases, Vol. 61, 01.12.2015, p. S618-S621.

Research output: Contribution to journalArticle

Ghannoum, Mahmoud ; Roilides, Emmanuel ; Katragkou, Aspasia ; Petraitis, Vidmantas ; Walsh, Thomas J. / The Role of Echinocandins in Candida Biofilm-Related Vascular Catheter Infections : In Vitro and in Vivo Model Systems. In: Clinical Infectious Diseases. 2015 ; Vol. 61. pp. S618-S621.
@article{b8e188e18bf04b75979e6c2cb0cb1e59,
title = "The Role of Echinocandins in Candida Biofilm-Related Vascular Catheter Infections: In Vitro and in Vivo Model Systems",
abstract = "Candida biofilm-associated infections of central venous catheters are a challenging therapeutic problem. Recent in vitro and in vivo studies of the structure, formation, pathogenesis, and treatment establish a rationale for new approaches to management of these tenacious infections.",
keywords = "anidulafungin, biofilm, caspofungin, echinocandin, micafungin",
author = "Mahmoud Ghannoum and Emmanuel Roilides and Aspasia Katragkou and Vidmantas Petraitis and Walsh, {Thomas J.}",
year = "2015",
month = "12",
day = "1",
doi = "10.1093/cid/civ815",
language = "English (US)",
volume = "61",
pages = "S618--S621",
journal = "Clinical Infectious Diseases",
issn = "1058-4838",
publisher = "Oxford University Press",

}

TY - JOUR

T1 - The Role of Echinocandins in Candida Biofilm-Related Vascular Catheter Infections

T2 - In Vitro and in Vivo Model Systems

AU - Ghannoum, Mahmoud

AU - Roilides, Emmanuel

AU - Katragkou, Aspasia

AU - Petraitis, Vidmantas

AU - Walsh, Thomas J.

PY - 2015/12/1

Y1 - 2015/12/1

N2 - Candida biofilm-associated infections of central venous catheters are a challenging therapeutic problem. Recent in vitro and in vivo studies of the structure, formation, pathogenesis, and treatment establish a rationale for new approaches to management of these tenacious infections.

AB - Candida biofilm-associated infections of central venous catheters are a challenging therapeutic problem. Recent in vitro and in vivo studies of the structure, formation, pathogenesis, and treatment establish a rationale for new approaches to management of these tenacious infections.

KW - anidulafungin

KW - biofilm

KW - caspofungin

KW - echinocandin

KW - micafungin

UR - http://www.scopus.com/inward/record.url?scp=84950291922&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84950291922&partnerID=8YFLogxK

U2 - 10.1093/cid/civ815

DO - 10.1093/cid/civ815

M3 - Article

C2 - 26567279

AN - SCOPUS:84950291922

VL - 61

SP - S618-S621

JO - Clinical Infectious Diseases

JF - Clinical Infectious Diseases

SN - 1058-4838

ER -