The role of depressive symptoms in predicting sex with multiple and high-risk partners

Chyvette T. Williams, Carl A. Latkin

Research output: Contribution to journalArticlepeer-review

57 Scopus citations


Existing research examining the role of psychopathology on HIV risk behaviors has relied heavily upon cross-sectional data, making it difficult to assess causal relationships. This paper uses longitudinal data to examine the relationship between depressive symptoms and sexual risk behaviors in a community sample of 332 inner-city drug users. Results from repeated measures analysis using generalized estimating equations suggest that high depressive symptoms may be causally related to having sex with multiple partners (odds ratio = 1.55, CI: 1.12, 2.14) and having sex with injection drug users (odds ratio = 1.57, CI: 1.11, 2.22) and crack users (odds ratio = 1.37, CI: 1.02, 1.86). Findings support greater attention to depressive symptoms in HIV prevention interventions for illicit drug users to reduce sexual risk behaviors.

Original languageEnglish (US)
Pages (from-to)69-73
Number of pages5
JournalJournal of Acquired Immune Deficiency Syndromes
Issue number1
StatePublished - Jan 1 2005


  • Depressive symptoms
  • Drug users
  • HIV risk
  • Sexual risk behaviors

ASJC Scopus subject areas

  • Infectious Diseases
  • Pharmacology (medical)


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