The role of cytotoxic chemotherapy in prostate cancer: A critical reevaluation 20 years later

Research output: Contribution to journalReview articlepeer-review

Abstract

In this review, we describe how clinical investigators addressed some of the challenges in prostate cancer chemotherapy trials 20 years ago, and we indicate what has evolved in the field since that time. We consider the impact that prostate-specific antigen measurement had in this setting, evolving clinical paradigms, multidisciplinary programs, and the current armamentarium of cancer treatment, including targeted molecular therapy, for patients with hormone-refractory disease.

Original languageEnglish (US)
Pages (from-to)853-862
Number of pages10
JournalONCOLOGY
Volume20
Issue number8
StatePublished - Dec 1 2006

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

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