The role of Color Doppler sonography in predicting malignacy in thyroid nodules

Sudhir Kathuria, Jyotsna Sen, Rajeev Sen, Sunita Singh, Rohtas Kumar Yadav, Jai Parkash Sharma

Research output: Contribution to journalArticlepeer-review


Forty patients of thyroid nodules were evaluated by gray scale and Color Doppler sonography. Pathological diagnoses established were colloid nodules (27), adenoma (2), carcinoma (10) and lymphoma (1). Microcalcification, halo sing, echogenicity, patterns of blood flow in the nodule: Type I (absence), Type II (mainly perinodular), Type III (marked intranodular) and RI were found useful parameters. Pathology correlation was established in all the cases and statistical evaluation was performed. A combination of microcalcitication, absent-halo-sing and Type III pattern or Type II pattern with RI>.75 predicted carcinome pesitively in 85.7%, negatively in 86.6% with an overall specificity of 96.2% and sensitivity of 60%. Irrespective of microcalcification and absent-halo-sing, sonographic features of local invasion, altered echotexture in enlarged lymph nodes, RI>.75 in a predominantly cystic nodule provided diagnostic clues in carcinoma. Smooth regular halo with "spoke-and-wheel" appearance on color Doppler suggested a diagnosis of adenome whereas hypoechoic lobulated avascular mass with heterogenous echotexture of adjacent thyroid parenchyme due to chronic thyroiditis indicated lymphoma.

Original languageEnglish (US)
Pages (from-to)8-14
Number of pages7
JournalUltrasound International
Issue number1
StatePublished - Jan 2003


  • Color doppler
  • Malignancy
  • Sonography
  • Thytoid nodules

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging


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