The retinal oxysterol pathway: A unifying hypothesis for the cause of aqe-related macular degeneration

Norman B. Javitt; Jonathan C. Javitt

doi:10.1097/ICU.0b013e32832af468

The retinal oxysterol pathway: A unifying hypothesis for the cause of aqe-related macular degeneration

Norman B. Javitt, Jonathan C. Javitt

School of Medicine

Research output: Contribution to journal › Article › peer-review

36 Scopus citations

Abstract

The toxic role of 7-ketocholesterol and existing pathways for its neutralization may point the way to a unified theory that explains the cause of age-related macular degeneration and points towards novel therapeutic interventions.

Original language	English (US)
Pages (from-to)	151-157
Number of pages	7
Journal	Current Opinion in Ophthalmology
Volume	20
Issue number	3
DOIs	https://doi.org/10.1097/ICU.0b013e32832af468
State	Published - May 2009

Keywords

Age-related macular degeneration
Ketocholesterol
Light toxicity
Oxysterol
Photooxidation

ASJC Scopus subject areas

Ophthalmology

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10.1097/ICU.0b013e32832af468

Cite this

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title = "The retinal oxysterol pathway: A unifying hypothesis for the cause of aqe-related macular degeneration",

abstract = "The toxic role of 7-ketocholesterol and existing pathways for its neutralization may point the way to a unified theory that explains the cause of age-related macular degeneration and points towards novel therapeutic interventions.",

keywords = "Age-related macular degeneration, Ketocholesterol, Light toxicity, Oxysterol, Photooxidation",

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The retinal oxysterol pathway: A unifying hypothesis for the cause of aqe-related macular degeneration

Abstract

Keywords

ASJC Scopus subject areas

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